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Anticoagulation for atrial fibrillation in heart failure patients: balancing between Scylla and Charybdis

The management of heart failure (HF) and atrial fibrillation (AF) in real-world practice remains a debating issue, while the number of HF patients with AF increase dramatically. While it is unclear if rhythm or rate control therapy is more beneficial and under which circumstances, anticoagulation th...

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Detalles Bibliográficos
Autores principales: Tsigkas, Grigorios, Apostolos, Anastasiοs, Despotopoulos, Stefanos, Vasilagkos, Georgios, Papageorgiou, Angeliki, Kallergis, Eleftherios, Leventopoulos, Georgios, Mplani, Virginia, Koniari, Ioanna, Velissaris, Dimitrios, Parissis, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185440/
https://www.ncbi.nlm.nih.gov/pubmed/34149824
http://dx.doi.org/10.11909/j.issn.1671-5411.2021.05.006
Descripción
Sumario:The management of heart failure (HF) and atrial fibrillation (AF) in real-world practice remains a debating issue, while the number of HF patients with AF increase dramatically. While it is unclear if rhythm or rate control therapy is more beneficial and under which circumstances, anticoagulation therapy is the cornerstone of the AF-HF patients’ approach. Vitamin-K antagonists were the gold-standard during the past, but currently their usage is limited in specific conditions. Non-vitamin K oral anticoagulants (NOACs) have gained ground during the last ten years and considered as gold-standard of a wide spectrum of HF phenotypes. The current manuscript aims to review the current literature regarding the indications and the optimal choice and usage of NOACs in HF patients with AF.