Cargando…

Binding between ROCK1 and DCTN2 triggers diabetes-associated centrosome amplification in colon cancer cells

Type 2 diabetes increases the risk various types of cancer and is associated with a poor prognosis therein. There is also evidence that the disease is associated with cancer metastasis. Centrosome amplification can initiate tumorigenesis with metastasis in vivo and increase the invasiveness of cance...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yuan Fei, Shi, Lin Jie, Wang, Pu, Wang, Jia Wen, Shi, Guang Yi, Lee, Shao Chin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185503/ https://www.ncbi.nlm.nih.gov/pubmed/34080666 http://dx.doi.org/10.3892/or.2021.8102

Ejemplares similares

Distinct prognostic value of dynactin subunit 4 (DCTN4) and diagnostic value of DCTN1, DCTN2, and DCTN4 in colon adenocarcinoma
por: Wang, Shijun, et al.
Publicado: (2018)

PCNA and JNK1‐Stat3 pathways respectively promotes and inhibits diabetes‐associated centrosome amplification by targeting at the ROCK1/14‐3‐3σ complex in human colon cancer HCT116 cells
por: Lu, Yu Cheng, et al.
Publicado: (2018)

Loss of KLF14 triggers centrosome amplification and tumorigenesis
por: Fan, Guangjian, et al.
Publicado: (2015)

DCTN1 mutations in Perry syndrome
por: Farrer, Matthew J., et al.
Publicado: (2009)

DCTN1 Binds to TDP-43 and Regulates TDP-43 Aggregation
por: Deshimaru, Manami, et al.
Publicado: (2021)

Cortical dynein drives centrosome clustering in cells with centrosome amplification
por: Mercadante, Dayna L., et al.
Publicado: (2023)

Antizyme Restrains Centrosome Amplification by Regulating the Accumulation of Mps1 at Centrosomes
por: Kasbek, Christopher, et al.
Publicado: (2010)

DCTN1 gene analysis in Chinese patients with sporadic amyotrophic lateral sclerosis
por: Liu, Xiangyi, et al.
Publicado: (2017)

Reduced levels of ALS gene DCTN1 induce motor defects in Drosophila
por: Borg, Rebecca, et al.
Publicado: (2023)

GPER1 links estrogens to centrosome amplification and chromosomal instability in human colon cells
por: Bühler, Miriam, et al.
Publicado: (2022)

Clinical implication of centrosome amplification and expression of centrosomal functional genes in multiple myeloma
por: Dementyeva, Elena, et al.
Publicado: (2013)

Overexpression of WDR62 is associated with centrosome amplification in human ovarian cancer
por: Zhang, Yu, et al.
Publicado: (2013)

HTLV-1 Tax: centrosome amplification and cancer
por: Pumfery, Anne, et al.
Publicado: (2006)

Targeting centrosome amplification, an Achilles' heel of cancer
por: Sabat-Pośpiech, Dorota, et al.
Publicado: (2019)

Centrosome amplification disrupts renal development and causes cystogenesis
por: Dionne, Lai Kuan, et al.
Publicado: (2018)

Loss of AMPKalpha1 Triggers Centrosome Amplification via PLK4 Upregulation in Mouse Embryonic Fibroblasts
por: Zhao, Qiang, et al.
Publicado: (2020)

The G(1 )phase Cdks regulate the centrosome cycle and mediate oncogene-dependent centrosome amplification
por: Harrison, Mary K, et al.
Publicado: (2011)

New phenotype of DCTN1‐related spectrum: early‐onset dHMN plus congenital foot deformity
por: Tian, Wo‐Tu, et al.
Publicado: (2020)

Cep131 overexpression promotes centrosome amplification and colon cancer progression by regulating Plk4 stability
por: Kim, Dong Hyun, et al.
Publicado: (2019)

The dynactin subunit DCTN1 controls osteoclastogenesis via the Cdc42/PAK2 pathway
por: Lee, Yong Deok, et al.
Publicado: (2020)

Centrosomal protein 120 promotes centrosome amplification and gastric cancer progression via USP54-mediated deubiquitination of PLK4
por: Zhang, Chenggang, et al.
Publicado: (2022)

A Clinical Overview of Centrosome Amplification in Human Cancers
por: Chan, Jason Yongsheng
Publicado: (2011)

Oncosuppressive functions of PIDD1 in response to centrosome amplification
por: Vitale, Ilio, et al.
Publicado: (2021)

Aberrant expression of maternal Plk1 and Dctn3 results in the developmental failure of human in-vivo- and in-vitro-matured oocytes
por: Fan, Yong, et al.
Publicado: (2015)

Analysis of the “centrosome-ome” identifies MCPH1 deletion as a cause of centrosome amplification in human cancer
por: Denu, Ryan A., et al.
Publicado: (2020)

Quantitative multi-parametric evaluation of centrosome declustering drugs: centrosome amplification, mitotic phenotype, cell cycle and death
por: Ogden, A, et al.
Publicado: (2014)

BRCA1 transports the DNA damage signal for CDDP‐induced centrosome amplification through the centrosomal Aurora A
por: Qi, Huicheng, et al.
Publicado: (2022)

The Rho-associated protein kinase p160ROCK is required for centrosome positioning
por: Chevrier, Véronique, et al.
Publicado: (2002)

Multiplying madly: Deacetylases take charge of centrosome duplication and amplification
por: Hung, Hui-Fang, et al.
Publicado: (2012)

Dynamics of centriole amplification in centrosome-depleted brain multiciliated progenitors
por: Mercey, Olivier, et al.
Publicado: (2019)

Patterns of selection against centrosome amplification in human cell lines
por: Dias Louro, Marco António, et al.
Publicado: (2021)

Molecular landscape and functional characterization of centrosome amplification in ovarian cancer
por: Sauer, Carolin M., et al.
Publicado: (2023)

Effectiveness of alectinib and osimertinib in a brain metastasized lung adenocarcinoma patient with concurrent EGFR mutations and DCTN1‐ALK fusion
por: Yin, Qiang, et al.
Publicado: (2021)

14-3-3γ Prevents Centrosome Amplification and Neoplastic Progression
por: Mukhopadhyay, Amitabha, et al.
Publicado: (2016)

Epstein–Barr virus particles induce centrosome amplification and chromosomal instability
por: Shumilov, Anatoliy, et al.
Publicado: (2017)

Inhibition of Cdk2 activity decreases Aurora-A kinase centrosomal localization and prevents centrosome amplification in breast cancer cells
por: LEONTOVICH, ALEXEY A., et al.
Publicado: (2013)

The SH2 domain and kinase activity of JAK2 target JAK2 to centrosome and regulate cell growth and centrosome amplification
por: Shahi, Aashirwad, et al.
Publicado: (2022)

Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis
por: Emond, Mary J, et al.
Publicado: (2012)

Non-centrosomal epidermal microtubules act in parallel to LET-502/ROCK to promote C. elegans elongation
por: Quintin, Sophie, et al.
Publicado: (2016)

Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification
por: Flanagan, Anne-Marie, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_6hmp0i7hquf263dmkphhnfh1nc