Cargando…

Sensitizing TRAIL-resistant A549 lung cancer cells and enhancing TRAIL-induced apoptosis with the antidepressant amitriptyline

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a cytokine with the potential to induce cancer cell-specific apoptosis with minimal toxicity to normal cells. Therefore, the resistance of certain cancer cells to TRAIL is a major concern and agents that can either enhance TRAIL capa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zinnah, K.M.A., Park, Sang-Youel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185507/ https://www.ncbi.nlm.nih.gov/pubmed/34080659 http://dx.doi.org/10.3892/or.2021.8095

Ejemplares similares

Enhancement of TRAIL-induced apoptosis by 5-fluorouracil requires activating Bax and p53 pathways in TRAIL-resistant lung cancers
por: Nazim, Uddin MD., et al.
Publicado: (2017)

Inhibition of autophagy flux by sertraline attenuates TRAIL resistance in lung cancer via death receptor 5 upregulation
por: Zinnah, Kazi Mohammad Ali, et al.
Publicado: (2020)

Overcoming Hypoxic-Resistance of Tumor Cells to TRAIL-Induced Apoptosis through Melatonin
por: Lee, You-Jin, et al.
Publicado: (2014)

Glipizide sensitizes lung cancer cells to TRAIL-induced apoptosis via Akt/mTOR/autophagy pathways
por: Nazim, Uddin MD., et al.
Publicado: (2017)

PPARγ activation by troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy flux
por: Nazim, Uddin MD., et al.
Publicado: (2017)

Attenuation of autophagy flux by 6-shogaol sensitizes human liver cancer cells to TRAIL-induced apoptosis via p53 and ROS
por: Nazim, Uddin MD., et al.
Publicado: (2019)

Neferine treatment enhances the TRAIL-induced apoptosis of human prostate cancer cells via autophagic flux and the JNK pathway
por: Nazim, Uddin Md, et al.
Publicado: (2020)

Ophiopogonin B sensitizes TRAIL-induced apoptosis through activation of autophagy flux and downregulates cellular FLICE-like inhibitory protein
por: Nazim, Uddin MD., et al.
Publicado: (2017)

Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL-induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species
por: Nazim, Uddin Md, et al.
Publicado: (2019)

Trailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer Cells
por: Trivedi, Rachana, et al.
Publicado: (2015)

Splicing reprogramming of TRAIL/DISC-components sensitizes lung cancer cells to TRAIL-mediated apoptosis
por: Voss, Oliver H., et al.
Publicado: (2021)

TRAIL-Induced Apoptosis in TRAIL-Resistant Breast Carcinoma Through Quercetin Cotreatment
por: Manouchehri, Jasmine M, et al.
Publicado: (2018)

5-allyl-7-gen-difluoromethoxychrysin enhances TRAIL-induced apoptosis in human lung carcinoma A549 cells
por: Xie, Zhao-Hui, et al.
Publicado: (2011)

Downregulation of c-FLIP and upregulation of DR-5 by cantharidin sensitizes TRAIL-mediated apoptosis in prostate cancer cells via autophagy flux
por: Nazim, Uddin Md, et al.
Publicado: (2020)

The emphysematous lung is abnormally sensitive to TRAIL-mediated apoptosis
por: Morissette, Mathieu C, et al.
Publicado: (2011)

Shikonin sensitizes A549 cells to TRAIL-induced apoptosis through the JNK, STAT3 and AKT pathways
por: Guo, Zhi Lan, et al.
Publicado: (2018)

Activation of autophagy flux by metformin downregulates cellular FLICE–like inhibitory protein and enhances TRAIL- induced apoptosis
por: Nazim, Uddin MD, et al.
Publicado: (2016)

Activation of autophagic flux by epigallocatechin gallate mitigates TRAIL-induced tumor cell apoptosis via down-regulation of death receptors
por: Kim, Sung-Wook, et al.
Publicado: (2016)

Herbal Medicines Showing Synergistic Effects with Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) against A549 TRAIL-resistant Lung Cancer Cells: A Screening Study
por: Chiang, Shuen Cheng, et al.
Publicado: (2018)

Role of phloretin as a sensitizer to TRAIL-induced apoptosis in colon cancer
por: Kim, Jung-Lim, et al.
Publicado: (2022)

TRAIL and curcumin codelivery nanoparticles enhance TRAIL-induced apoptosis through upregulation of death receptors
por: Yang, Xi, et al.
Publicado: (2017)

N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis
por: Estornes, Yann, et al.
Publicado: (2018)

N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death
por: Dufour, Florent, et al.
Publicado: (2017)

Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis
por: Chan, David Y. L., et al.
Publicado: (2007)

Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis
por: Murphy, Á. C., et al.
Publicado: (2013)

Andrographolide sensitizes prostate cancer cells to TRAIL-induced apoptosis
por: Wei, Ruo-Jing, et al.
Publicado: (2018)

Alternol Sensitizes Renal Carcinoma Cells to TRAIL-Induced Apoptosis
por: Ren, Yu, et al.
Publicado: (2021)

Author Correction: Bisphosphonate enhances TRAIL sensitivity to human osteosarcoma cells via death receptor 5 upregulation
por: Moon, Myung-Hee, et al.
Publicado: (2018)

The regulation of combined treatment-induced cell death with recombinant TRAIL and bortezomib through TRAIL signaling in TRAIL-resistant cells
por: Ryu, Sunhyo, et al.
Publicado: (2018)

HTNV Sensitizes Host Toward TRAIL-Mediated Apoptosis—A Pivotal Anti-hantaviral Role of TRAIL
por: Chen, Qing-Zhou, et al.
Publicado: (2020)

TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress
por: Dufour, Florent, et al.
Publicado: (2016)

Bufalin sensitizes human bladder carcinoma cells to TRAIL-mediated apoptosis
por: Kang, Kyung-Hwa, et al.
Publicado: (2017)

Induction of cellular prion protein (PrPc) under hypoxia inhibits apoptosis caused by TRAIL treatment
por: Park, Jin-Young, et al.
Publicado: (2015)

HIV Induces TRAIL Sensitivity in Hepatocytes
por: Babu, Challagundla K., et al.
Publicado: (2009)

Chalcones Enhance TRAIL-Induced Apoptosis in Prostate Cancer Cells
por: Szliszka, Ewelina, et al.
Publicado: (2009)

LPS promotes resistance to TRAIL-induced apoptosis in pancreatic cancer
por: Beyer, Katharina, et al.
Publicado: (2017)

Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs
por: Nalli, Ancy D., et al.
Publicado: (2018)

Targeting Death Receptor TRAIL-R2 by Chalcones for TRAIL-Induced Apoptosis in Cancer Cells
por: Szliszka, Ewelina, et al.
Publicado: (2012)

The ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastoma
por: van Roosmalen, Ingrid A M, et al.
Publicado: (2014)

TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes
por: Staniek, Julian, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_snrkmitb66rminp3pf2an4q96k