Cargando…

Total saponins from Rhizoma Panacis Majoris inhibit proliferation, induce cell cycle arrest and apoptosis and influence MAPK signalling pathways on the colorectal cancer cell

Colorectal cancer (CRC) ranks third in incidence and second in mortality among all types of cancer, and due to its insidious onset and lack of early symptoms, it is usually diagnosed at a later stage. Saponins, a class of compounds abundant in plants, have been reported to possess prominent anti-tum...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chang, Lu, Zhou, Rui, He, Yihan, Meng, Mei, Hu, Jinhang, Liu, Yanru, Pan, Yalei, Tang, Zhishu, Yue, Zhenggang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185512/ https://www.ncbi.nlm.nih.gov/pubmed/34080021 http://dx.doi.org/10.3892/mmr.2021.12181

Ejemplares similares

Anti-Rheumatoid Arthritic Effects of Paris Saponin VII in Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes and Adjuvant-Induced Arthritis in Rats
por: Meng, Mei, et al.
Publicado: (2021)

Rhizoma Paridis Saponins Induces Cell Cycle Arrest and Apoptosis in Non-Small Cell Lung Carcinoma A549 Cells
por: Zhang, Jue, et al.
Publicado: (2015)

A Novel Strategy for Quantitative Analysis of Major Ginsenosides in Panacis Japonici Rhizoma with a Standardized Reference Fraction
por: Meng, Fan-Cheng, et al.
Publicado: (2017)

The life-cycle of the avian haemosporidian parasite Haemoproteus majoris, with emphasis on the exoerythrocytic and sporogonic development
por: Ilgūnas, Mikas, et al.
Publicado: (2019)

A novel polysaccharide from Rhizoma panacis japonica exerts anti-inflammatory effects via STAT3 signal pathway
por: Li, Qiu, et al.
Publicado: (2018)

Total saponin of Dioscoreae hypoglaucae rhizoma ameliorates streptozotocin-induced diabetic nephropathy
por: Guo, Changrun, et al.
Publicado: (2016)

Analysis of saponins detoxification genes in Ilyonectria mors-panacis G3B inducing root rot of Panax notoginseng by RNA-Seq
por: Zeng, Guohong, et al.
Publicado: (2021)

Zwartia vadi sp. nov., a Novel Species of the GKS98 Cluster Isolated from a Stream, and the Reclassification of ‘Achromobacter Panacis’ as Zwartia panacis comb. nov
por: Park, Miri S., et al.
Publicado: (2023)

Machine learning methods to predict the cultivation age of Panacis Quinquefolii Radix
por: Hu, Xiaowen, et al.
Publicado: (2021)

Steroidal Saponins from the Roots and Rhizomes of Tupistra chinensis
por: Li, Yuze, et al.
Publicado: (2015)

Alfalfa saponins inhibit oxidative stress-induced cell apoptosis through the MAPK signaling pathway
por: Cui, Yalei, et al.
Publicado: (2021)

Local clouds: ionization, temperatures, electron densities and interfaces, from GHRS and IMAPS spectra of epsilon Canis Majoris
por: Gry, C, et al.
Publicado: (2001)

Effect of Rhizoma Paridis saponin on the pain behavior in a mouse model of cancer pain
por: Wang, Genbei, et al.
Publicado: (2018)

Paris Saponin I Sensitizes Gastric Cancer Cell Lines to Cisplatin via Cell Cycle Arrest and Apoptosis
por: Song, Shuichuan, et al.
Publicado: (2016)

Rhizoma Paridis total saponins alleviate H(2)O(2)-induced oxidative stress injury by upregulating the Nrf2 pathway
por: Zhao, Baocheng, et al.
Publicado: (2020)

Natural Deep Eutectic Solvents for the Extraction of Bioactive Steroidal Saponins from Dioscoreae Nipponicae Rhizoma
por: Yang, Gui-Ya, et al.
Publicado: (2021)

Studies on biotransformation mechanism of Fusarium sp. C39 to enhance saponin content of Paridis Rhizoma
por: Chen, Yiyang, et al.
Publicado: (2022)

Comparative Analysis of the Exo-Erythrocytic Development of Five Lineages of Haemoproteus majoris, a Common Haemosporidian Parasite of European Passeriform Birds
por: Duc, Mélanie, et al.
Publicado: (2023)

Discovery of a new primer set for detection and quantification of Ilyonectria mors-panacis in soils for ginseng cultivation
por: Farh, Mohamed El-Agamy, et al.
Publicado: (2019)

Anemarrhena asphodeloides Non-Steroidal Saponin Components Alter the Pharmacokinetic Profile of Its Steroidal Saponins in Rat
por: Tang, Zhishu, et al.
Publicado: (2015)

Rapid Determination of Saponins in the Honey-Fried Processing of Rhizoma Cimicifugae by Near Infrared Diffuse Reflectance Spectroscopy
por: Wu, Lun, et al.
Publicado: (2018)

Rhizoma Paridis saponins ameliorates hepatic fibrosis in rats by downregulating expression of angiogenesis-associated growth factors
por: Han, Yanquan, et al.
Publicado: (2019)

Comprehensive Genome Analysis on the Novel Species Sphingomonas panacis DCY99(T) Reveals Insights into Iron Tolerance of Ginseng
por: Kim, Yeon-Ju, et al.
Publicado: (2020)

Review of Constituents and Biological Activities of Triterpene Saponins from Glycyrrhizae Radix et Rhizoma and Its Solubilization Characteristics
por: Li, Feifei, et al.
Publicado: (2020)

Panacis Quinquefolii Radix: A Review of the Botany, Phytochemistry, Quality Control, Pharmacology, Toxicology and Industrial Applications Research Progress
por: Yang, Liu, et al.
Publicado: (2020)

ZHX1 Inhibits Gastric Cancer Cell Growth through Inducing Cell-Cycle Arrest and Apoptosis
por: Ma, Xingjie, et al.
Publicado: (2016)

Effect of Soil and Root Extracts on the Innate Immune Response of American Ginseng (Panax quinquefolius) to Root Rot Caused by Ilyonectria mors-panacis
por: Behdarvandi, Behrang, et al.
Publicado: (2023)

Synthetic Tryptanthrin Derivatives Induce Cell Cycle Arrest and Apoptosis via Akt and MAPKs in Human Hepatocellular Carcinoma Cells
por: Gao, Jing-Yan, et al.
Publicado: (2021)

Shikonin derivatives cause apoptosis and cell cycle arrest in human chondrosarcoma cells via death receptors and MAPK regulation
por: Lohberger, Birgit, et al.
Publicado: (2022)

The effects of Rhizoma Curculiginis and Rhizoma Drynariae extracts on bones
por: Wong, Ricky WK, et al.
Publicado: (2007)

Cell cycle arrest is not senescence
por: Blagosklonny, Mikhail V.
Publicado: (2011)

Antiatherosclerosis Properties of Total Saponins of Garlic in Rats
por: Miao, Qing, et al.
Publicado: (2020)

Rhizoma Paridis Saponins Suppresses Tumor Growth in a Rat Model of N-Nitrosomethylbenzylamine-Induced Esophageal Cancer by Inhibiting Cyclooxygenases-2 Pathway
por: Yan, Shu, et al.
Publicado: (2015)

Molecular Role of EGFR-MAPK Pathway in Patchouli Alcohol-Induced Apoptosis and Cell Cycle Arrest on A549 Cells In Vitro and In Vivo
por: Lu, XinGang, et al.
Publicado: (2016)

Podophyllotoxin Induces ROS-Mediated Apoptosis and Cell Cycle Arrest in Human Colorectal Cancer Cells via p38 MAPK Signaling
por: Lee, Seung-On, et al.
Publicado: (2021)

Isolinderalactone Induces Apoptosis, Autophagy, Cell Cycle Arrest and MAPK Activation through ROS–Mediated Signaling in Colorectal Cancer Cell Lines
por: Chen, Jith-Shyan, et al.
Publicado: (2023)

Anti-inflammation effects of the total saponin fraction from Dioscorea nipponica Makino on rats with gouty arthritis by influencing MAPK signalling pathway
por: Zhou, Qi, et al.
Publicado: (2020)

Effects of Alismatis Rhizoma and Rhizoma Smilacis Glabrae Decoction on Hyperuricemia in Rats
por: Cheng, Shupin, et al.
Publicado: (2019)

A Compositive Strategy to Study the Pharmacokinetics of TCMs: Taking Coptidis Rhizoma, and Coptidis Rhizoma-Glycyrrhizae Radix et Rhizoma as Examples
por: Li, Qiao, et al.
Publicado: (2018)

The molecular architecture of cell cycle arrest
por: Stallaert, Wayne, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7ks19nbqh4t7ij070r6hjkc9d5