Cargando…

DeepFoG: An IMU-Based Detection of Freezing of Gait Episodes in Parkinson’s Disease Patients via Deep Learning

Freezing of Gait (FoG) is a movement disorder that mostly appears in the late stages of Parkinson’s Disease (PD). It causes incapability of walking, despite the PD patient’s intention, resulting in loss of coordination that increases the risk of falls and injuries and severely affects the PD patient...

Descripción completa

Detalles Bibliográficos
Autores principales: Bikias, Thomas, Iakovakis, Dimitrios, Hadjidimitriou, Stelios, Charisis, Vasileios, Hadjileontiadis, Leontios J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185568/
https://www.ncbi.nlm.nih.gov/pubmed/34113654
http://dx.doi.org/10.3389/frobt.2021.537384
_version_ 1783704814784348160
author Bikias, Thomas
Iakovakis, Dimitrios
Hadjidimitriou, Stelios
Charisis, Vasileios
Hadjileontiadis, Leontios J.
author_facet Bikias, Thomas
Iakovakis, Dimitrios
Hadjidimitriou, Stelios
Charisis, Vasileios
Hadjileontiadis, Leontios J.
author_sort Bikias, Thomas
collection PubMed
description Freezing of Gait (FoG) is a movement disorder that mostly appears in the late stages of Parkinson’s Disease (PD). It causes incapability of walking, despite the PD patient’s intention, resulting in loss of coordination that increases the risk of falls and injuries and severely affects the PD patient’s quality of life. Stress, emotional stimulus, and multitasking have been encountered to be associated with the appearance of FoG episodes, while the patient’s functionality and self-confidence are constantly deteriorating. This study suggests a non-invasive method for detecting FoG episodes, by analyzing inertial measurement unit (IMU) data. Specifically, accelerometer and gyroscope data from 11 PD subjects, as captured from a single wrist-worn IMU sensor during continuous walking, are processed via Deep Learning for window-based detection of the FoG events. The proposed approach, namely DeepFoG, was evaluated in a Leave-One-Subject-Out (LOSO) cross-validation (CV) and 10-fold CV fashion schemes against its ability to correctly estimate the existence or not of a FoG episode at each data window. Experimental results have shown that DeepFoG performs satisfactorily, as it achieves 83%/88% and 86%/90% sensitivity/specificity, for LOSO CV and 10-fold CV schemes, respectively. The promising performance of the proposed DeepFoG reveals the potentiality of single-arm IMU-based real-time FoG detection that could guide effective interventions via stimuli, such as rhythmic auditory stimulation (RAS) and hand vibration. In this way, DeepFoG may scaffold the elimination of risk of falls in PD patients, sustaining their quality of life in everyday living activities.
format Online
Article
Text
id pubmed-8185568
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-81855682021-06-09 DeepFoG: An IMU-Based Detection of Freezing of Gait Episodes in Parkinson’s Disease Patients via Deep Learning Bikias, Thomas Iakovakis, Dimitrios Hadjidimitriou, Stelios Charisis, Vasileios Hadjileontiadis, Leontios J. Front Robot AI Robotics and AI Freezing of Gait (FoG) is a movement disorder that mostly appears in the late stages of Parkinson’s Disease (PD). It causes incapability of walking, despite the PD patient’s intention, resulting in loss of coordination that increases the risk of falls and injuries and severely affects the PD patient’s quality of life. Stress, emotional stimulus, and multitasking have been encountered to be associated with the appearance of FoG episodes, while the patient’s functionality and self-confidence are constantly deteriorating. This study suggests a non-invasive method for detecting FoG episodes, by analyzing inertial measurement unit (IMU) data. Specifically, accelerometer and gyroscope data from 11 PD subjects, as captured from a single wrist-worn IMU sensor during continuous walking, are processed via Deep Learning for window-based detection of the FoG events. The proposed approach, namely DeepFoG, was evaluated in a Leave-One-Subject-Out (LOSO) cross-validation (CV) and 10-fold CV fashion schemes against its ability to correctly estimate the existence or not of a FoG episode at each data window. Experimental results have shown that DeepFoG performs satisfactorily, as it achieves 83%/88% and 86%/90% sensitivity/specificity, for LOSO CV and 10-fold CV schemes, respectively. The promising performance of the proposed DeepFoG reveals the potentiality of single-arm IMU-based real-time FoG detection that could guide effective interventions via stimuli, such as rhythmic auditory stimulation (RAS) and hand vibration. In this way, DeepFoG may scaffold the elimination of risk of falls in PD patients, sustaining their quality of life in everyday living activities. Frontiers Media S.A. 2021-05-07 /pmc/articles/PMC8185568/ /pubmed/34113654 http://dx.doi.org/10.3389/frobt.2021.537384 Text en Copyright © 2021 Bikias, Iakovakis, Hadjidimitriou, Charisis and Hadjileontiadis. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Robotics and AI
Bikias, Thomas
Iakovakis, Dimitrios
Hadjidimitriou, Stelios
Charisis, Vasileios
Hadjileontiadis, Leontios J.
DeepFoG: An IMU-Based Detection of Freezing of Gait Episodes in Parkinson’s Disease Patients via Deep Learning
title DeepFoG: An IMU-Based Detection of Freezing of Gait Episodes in Parkinson’s Disease Patients via Deep Learning
title_full DeepFoG: An IMU-Based Detection of Freezing of Gait Episodes in Parkinson’s Disease Patients via Deep Learning
title_fullStr DeepFoG: An IMU-Based Detection of Freezing of Gait Episodes in Parkinson’s Disease Patients via Deep Learning
title_full_unstemmed DeepFoG: An IMU-Based Detection of Freezing of Gait Episodes in Parkinson’s Disease Patients via Deep Learning
title_short DeepFoG: An IMU-Based Detection of Freezing of Gait Episodes in Parkinson’s Disease Patients via Deep Learning
title_sort deepfog: an imu-based detection of freezing of gait episodes in parkinson’s disease patients via deep learning
topic Robotics and AI
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185568/
https://www.ncbi.nlm.nih.gov/pubmed/34113654
http://dx.doi.org/10.3389/frobt.2021.537384
work_keys_str_mv AT bikiasthomas deepfoganimubaseddetectionoffreezingofgaitepisodesinparkinsonsdiseasepatientsviadeeplearning
AT iakovakisdimitrios deepfoganimubaseddetectionoffreezingofgaitepisodesinparkinsonsdiseasepatientsviadeeplearning
AT hadjidimitrioustelios deepfoganimubaseddetectionoffreezingofgaitepisodesinparkinsonsdiseasepatientsviadeeplearning
AT charisisvasileios deepfoganimubaseddetectionoffreezingofgaitepisodesinparkinsonsdiseasepatientsviadeeplearning
AT hadjileontiadisleontiosj deepfoganimubaseddetectionoffreezingofgaitepisodesinparkinsonsdiseasepatientsviadeeplearning