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BRCA mutation rate and characteristics of prostate tumor in breast and ovarian cancer families: analysis of 6,591 Italian pedigrees

OBJECTIVE: As prostate cancer (PrC) shows a BRCA mutation rate as high as 30%, it becomes crucial to find the optimal selection criteria for genetic testing. The primary objective of this study was to evaluate the BRCA mutation rate in families with PrC associated with breast and/or ovarian cancers;...

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Detalles Bibliográficos
Autores principales: Cortesi, Laura, Domati, Federica, Guida, Annalisa, Marchi, Isabella, Toss, Angela, Barbieri, Elena, Marcheselli, Luigi, Venturelli, Marta, Piana, Simonetta, Cirilli, Claudia, Federico, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185862/
https://www.ncbi.nlm.nih.gov/pubmed/33710808
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0481