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Interphase Chromosomes in Replicative Senescence: Chromosome Positioning as a Senescence Biomarker and the Lack of Nuclear Motor-Driven Chromosome Repositioning in Senescent Cells

This study demonstrates, and confirms, that chromosome territory positioning is altered in primary senescent human dermal fibroblasts (HDFs). The chromosome territory positioning pattern is very similar to that found in HDFs made quiescent either by serum starvation or confluence; but not completely...

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Detalles Bibliográficos
Autores principales: Mehta, Ishita S., Riyahi, Kumars, Pereira, Rita Torres, Meaburn, Karen J., Figgitt, Martin, Kill, Ian R., Eskiw, Christopher H., Bridger, Joanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185894/
https://www.ncbi.nlm.nih.gov/pubmed/34113611
http://dx.doi.org/10.3389/fcell.2021.640200