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Loss of direct adrenergic innervation after peripheral nerve injury causes lymph node expansion through IFN-γ

Peripheral nerve injury can cause debilitating disease and immune cell–mediated destruction of the affected nerve. While the focus has been on the nerve-regenerative response, the effect of loss of innervation on lymph node function is unclear. Here, we show that the popliteal lymph node (popLN) rec...

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Detalles Bibliográficos
Autores principales: Chen, Chien-Sin, Weber, Jasmin, Holtkamp, Stephan Jonas, Ince, Louise Madeleine, de Juan, Alba, Wang, Chen, Lutes, Lydia, Barnoud, Coline, Kizil, Burak, Hergenhan, Sophia Martina, Salvermoser, Johanna, Lasch, Manuel, Deindl, Elisabeth, Schraml, Barbara, Baumjohann, Dirk, Scheiermann, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185988/
https://www.ncbi.nlm.nih.gov/pubmed/34086056
http://dx.doi.org/10.1084/jem.20202377