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Generating CAR T cells from tumor-infiltrating lymphocytes

Background: Tumor-infiltrating lymphocytes (TILs) and chimeric antigen receptor (CAR) T-cell therapies have demonstrated promising, though limited, efficacy against melanoma. Methods: We designed a model system to explore the efficacy of dual specific T cells derived from melanoma patient TILs by tr...

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Detalles Bibliográficos
Autores principales:	Mills, Jane K., Henderson, Melissa A., Giuffrida, Lauren, Petrone, Pasquale, Westwood, Jennifer A., Darcy, Phillip K., Neeson, Paul J., Kershaw, Michael H., Gyorki, David E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186112/ https://www.ncbi.nlm.nih.gov/pubmed/34159293 http://dx.doi.org/10.1177/25151355211017119

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