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Nicotine promotes the development of oral leukoplakia via regulating peroxiredoxin 1 and its binding proteins
Tobacco can induce reactive oxygen species (ROS) production extensively in cells, which is a major risk factor for oral leukoplakia (OLK) development. Peroxiredoxin 1 (Prx1) is a key antioxidant protein, upregulated in a variety of malignant tumors. We previously found that nicotine, the main ingred...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Associação Brasileira de Divulgação Científica
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186375/ https://www.ncbi.nlm.nih.gov/pubmed/34076143 http://dx.doi.org/10.1590/1414-431X2020e10931 |