Cargando…

Oxidized low-density lipoprotein stimulates dendritic cells maturation via LOX-1-mediated MAPK/NF-κB pathway

Dendritic cells (DCs) play a crucial role as central orchestrators of immune system response in atherosclerosis initiation and progression. Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is involved in the immune maturation of DCs, but the underlying mechanisms remain unclear. We is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, D., Gao, W., Lu, H., Qian, J.Y., Ge, J.B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Associação Brasileira de Divulgação Científica 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186376/ https://www.ncbi.nlm.nih.gov/pubmed/34076144 http://dx.doi.org/10.1590/1414-431X2021e11062

Ejemplares similares

Rapamycin Inhibits Oxidized Low Density Lipoprotein Uptake in Human Umbilical Vein Endothelial Cells via mTOR/NF-κB/LOX-1 Pathway
por: Zhou, Yan-De, et al.
Publicado: (2016)

Structure-based Design Targeted at LOX-1, a Receptor for Oxidized Low-Density Lipoprotein
por: Thakkar, Shraddha, et al.
Publicado: (2015)

Olmesartan Attenuates the Impairment of Endothelial Cells Induced by Oxidized Low Density Lipoprotein through Downregulating Expression of LOX-1
por: Zhang, Hua, et al.
Publicado: (2012)

Proteolytic Regulation of the Lectin-Like Oxidized Lipoprotein Receptor LOX-1
por: Mentrup, Torben, et al.
Publicado: (2021)

Polysaccharide isolated from seeds of Plantago asiatica L. induces maturation of dendritic cells through MAPK and NF-κB pathway
por: Jiang, LeMing, et al.
Publicado: (2018)

Role of LOX-1 and ROS in oxidized low-density lipoprotein induced epithelial-mesenchymal transition of NRK52E
por: Wang, Rui, et al.
Publicado: (2010)

Oxidized Low-Density Lipoprotein-Deteriorated Psoriasis Is Associated with the Upregulation of Lox-1 Receptor and Il-23 Expression In Vivo and In Vitro
por: Shih, Chun-Ming, et al.
Publicado: (2018)

Native and Oxidized Low-Density Lipoproteins Increase the Expression of the LDL Receptor and the LOX-1 Receptor, Respectively, in Arterial Endothelial Cells
por: Catar, Rusan, et al.
Publicado: (2022)

LOX-1 mediates inflammatory activation of microglial cells through the p38-MAPK/NF-κB pathways under hypoxic-ischemic conditions
por: Aoki, Yoshinori, et al.
Publicado: (2023)

Chlorella sorokiniana-Induced Activation and Maturation of Human Monocyte-Derived Dendritic Cells through NF-κB and PI3K/MAPK Pathways
por: Chou, Nien-Tzu, et al.
Publicado: (2012)

High-Density Lipoprotein Prevents Endoplasmic Reticulum Stress-Induced Downregulation of Liver LOX-1 Expression
por: Hong, Dan, et al.
Publicado: (2015)

Apolipoprotein CIII regulates lipoprotein-associated phospholipase A(2) expression via the MAPK and NFκB pathways
por: Han, Xiaolei, et al.
Publicado: (2015)

Oxidized Low-Density Lipoprotein Induces Apoptosis in Cultured Neonatal Rat Cardiomyocytes by Modulating the TLR4/NF-κB Pathway
por: Wang, Xiantao, et al.
Publicado: (2016)

Hyperoside inhibits the effects induced by oxidized low-density lipoprotein in vascular smooth muscle cells via oxLDL-LOX-1-ERK pathway
por: Zhang, Zhengyu, et al.
Publicado: (2017)

Serum Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 (sLOX-1) Is Associated with Atherosclerosis Severity in Coronary Artery Disease
por: Kott, Katharine A., et al.
Publicado: (2023)

NF-κB activation triggers NK-cell stimulation by monocyte-derived dendritic cells
por: Bosch, Naomi C., et al.
Publicado: (2019)

Klotho ameliorates oxidized low density lipoprotein (ox-LDL)-induced oxidative stress via regulating LOX-1 and PI3K/Akt/eNOS pathways
por: Yao, Yansheng, et al.
Publicado: (2017)

Liver X Receptor Agonist Inhibits Oxidized Low-Density Lipoprotein Induced Choroidal Neovascularization via the NF-κB Signaling Pathway
por: Wu, Tong, et al.
Publicado: (2023)

Tyloxapol inhibits RANKL-stimulated osteoclastogenesis and ovariectomized-induced bone loss by restraining NF-κB and MAPK activation
por: Guo, Wen, et al.
Publicado: (2021)

Chronic Aerobic Exercise Decreases Lectin-Like Low Density Lipoprotein (LOX-1) Receptor Expression in Heart of Diabetic Rat
por: Riahi, Simin, et al.
Publicado: (2016)

Electronegative Low-Density Lipoprotein Increases C-Reactive Protein Expression in Vascular Endothelial Cells through the LOX-1 Receptor
por: Chu, Chih-Sheng, et al.
Publicado: (2013)

Human electronegative low-density lipoprotein modulates cardiac repolarization via LOX-1-mediated alteration of sarcolemmal ion channels
por: Lee, An-Sheng, et al.
Publicado: (2017)

Anti-inflammation of isoliquiritigenin via the inhibition of NF-κB and MAPK in LPS-stimulated MAC-T cells
por: Li, Manman, et al.
Publicado: (2022)

Berberine alleviates oxidized low‐density lipoprotein‐induced macrophage activation by downregulating galectin‐3 via the NF‐κB and AMPK signaling pathways
por: Pei, ChongZhe, et al.
Publicado: (2018)

Protective effect of sonic hedgehog against oxidized low-density lipoprotein-induced endothelial apoptosis: Involvement of NF-κB and Bcl-2 signaling
por: Huang, Huashan, et al.
Publicado: (2020)

Protective effect of sonic hedgehog against oxidized low-density lipoprotein-induced endothelial apoptosis: Involvement of NF-κB and Bcl-2 signaling
por: Huang, Huashan, et al.
Publicado: (2020)

Circulating Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 (sLOX-1): A Diagnostic Indicator across the Spectrum of Acute Coronary Syndrome
por: Kumar, Sandeep, et al.
Publicado: (2021)

Mannose-Binding Lectin Reduces Oxidized Low-Density Lipoprotein Induced Vascular Endothelial Cells Injury by Inhibiting LOX1-ox-LDL Binding and Modulating Autophagy
por: Zhou, Xuelian, et al.
Publicado: (2023)

Aspirin Attenuates Cardiac Allograft Rejection by Inhibiting the Maturation of Dendritic Cells via the NF-κB Signaling Pathway
por: Zhang, Xi, et al.
Publicado: (2021)

Low-Density Lipoproteins Oxidation and Endometriosis
por: Polak, Grzegorz, et al.
Publicado: (2013)

Enhanced survival of BCG-stimulated dendritic cells: involvement of anti-apoptotic proteins and NF-κB
por: Kumar, Pawan, et al.
Publicado: (2018)

Ursolic Acid Attenuates Atherosclerosis in ApoE(−/−) Mice: Role of LOX-1 Mediated by ROS/NF-κB Pathway
por: Li, Qiu, et al.
Publicado: (2018)

Trichosanthes kirilowii lectin alleviates diabetic nephropathy by inhibiting the LOX1/NF-κB/caspase-9 signaling pathway
por: Lu, Jiandong, et al.
Publicado: (2018)

High-Density Lipoprotein Suppresses Neutrophil Extracellular Traps Enhanced by Oxidized Low-Density Lipoprotein or Oxidized Phospholipids
por: Ohinata, Hitomi, et al.
Publicado: (2022)

Exosomes derived from mature dendritic cells increase endothelial inflammation and atherosclerosis via membrane TNF‐α mediated NF‐κB pathway
por: Gao, Wei, et al.
Publicado: (2016)

Human adenovirus type 7 subunit vaccine induces dendritic cell maturation through the TLR4/NF-κB pathway is highly immunogenic
por: Li, Yaru, et al.
Publicado: (2023)

Dysiarenone from Marine Sponge Dysidea arenaria Attenuates ROS and Inflammation via Inhibition of 5-LOX/NF-κB/MAPKs and Upregulation of Nrf-2/OH-1 in RAW 264.7 Macrophages
por: Hu, Tian-Yong, et al.
Publicado: (2021)

Antithrombin prevents proinflammatory activation via NFκ and MAPK signaling pathways
por: Oelschläger, C, et al.
Publicado: (2002)

Electronegative Low-Density Lipoprotein L5 Impairs Viability and NGF-Induced Neuronal Differentiation of PC12 Cells via LOX-1
por: Wang, Jiz-Yuh, et al.
Publicado: (2017)

ETS variant transcription factor 6 enhances oxidized low-density lipoprotein-induced inflammatory response in atherosclerotic macrophages via activating NF-κB signaling
por: Xiong, Xiaofang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qnhuil9ed9895onmi6cldmk26o