Cargando…

Java application for cytoskeleton filament characterization (JACFC)

JACFC is a Java web application (http://neuronanobiophysics.utsa.edu/) that provides both experts and non-experts in the field suitable tools for elucidating the molecular mechanisms modulating the electrical signal propagation, stability, and bundle formation of microtubules and actin filaments und...

Descripción completa

Detalles Bibliográficos
Autor principal: Marucho, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186427/
https://www.ncbi.nlm.nih.gov/pubmed/34109318
http://dx.doi.org/10.1016/j.simpa.2021.100072
Descripción
Sumario:JACFC is a Java web application (http://neuronanobiophysics.utsa.edu/) that provides both experts and non-experts in the field suitable tools for elucidating the molecular mechanisms modulating the electrical signal propagation, stability, and bundle formation of microtubules and actin filaments under different molecular (wild type, isoforms, mutants) and environmental (physiological and pathological) conditions. This acknowledgment might reveal the potential role of cytoskeleton filaments in neuronal activities, including molecular-level processing of information and neural regeneration. Molecular understanding of the polyelectrolyte properties of bionanowires, is also crucial for development of reliability, highly functioning small devices with biotechnological applications such as bionanosensors and computing bionanoprocessors.