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β-Glucan-stimulated neutrophil secretion of IL-1α is independent of GSDMD and mediated through extracellular vesicles

Neutrophils are an important source of interleukin (IL)-1β and other cytokines because they are recruited to sites of infection and inflammation in high numbers. Although secretion of processed, bioactive IL-1β by neutrophils is dependent on NLRP3 and Gasdermin D (GSDMD), IL-1α secretion by neutroph...

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Detalles Bibliográficos
Autores principales: Ratitong, Bridget, Marshall, Michaela, Pearlman, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186457/
https://www.ncbi.nlm.nih.gov/pubmed/34010648
http://dx.doi.org/10.1016/j.celrep.2021.109139