Adenosine/TGFβ axis in regulation of mammary fibroblast functions

Cancer associated fibroblasts (CAF) play a key role in cancer progression and metastasis. Diminished TGFβ response on CAF correlates with poor outcome and recurrence in cancer patients. Mechanisms behind lost TGFβ signaling on CAF are poorly understood, but, utilizing MMTV-PyMT mouse model, we have...

Descripción completa

Detalles Bibliográficos
Autores principales: Vasiukov, Georgii, Menshikh, Anna, Owens, Philip, Novitskaya, Tatiana, Hurley, Paula, Blackwell, Timothy, Feoktistov, Igor, Novitskiy, Sergey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186761/
https://www.ncbi.nlm.nih.gov/pubmed/34101732
http://dx.doi.org/10.1371/journal.pone.0252424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186761/
https://www.ncbi.nlm.nih.gov/pubmed/34101732
http://dx.doi.org/10.1371/journal.pone.0252424

Ejemplares similares