Cargando…

RSC primes the quiescent genome for hypertranscription upon cell-cycle re-entry

Quiescence is a reversible G(0) state essential for differentiation, regeneration, stem-cell renewal, and immune cell activation. Necessary for long-term survival, quiescent chromatin is compact, hypoacetylated, and transcriptionally inactive. How transcription activates upon cell-cycle re-entry is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cucinotta, Christine E, Dell, Rachel H, Braceros, Keean CA, Tsukiyama, Toshio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186906/ https://www.ncbi.nlm.nih.gov/pubmed/34042048 http://dx.doi.org/10.7554/eLife.67033

Ejemplares similares

Local chromatin fiber folding represses transcription and loop extrusion in quiescent cells
por: Swygert, Sarah G, et al.
Publicado: (2021)

The chromatin remodelers RSC and ISW1 display functional and chromatin-based promoter antagonism
por: Parnell, Timothy J, et al.
Publicado: (2015)

Histone H2B ubiquitylation represses gametogenesis by opposing RSC-dependent chromatin remodeling at the ste11 master regulator locus
por: Materne, Philippe, et al.
Publicado: (2016)

The nucleosome DNA entry-exit site is important for transcription termination and prevention of pervasive transcription
por: Hildreth, A Elizabeth, et al.
Publicado: (2020)

Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle
por: Friman, Elias T, et al.
Publicado: (2019)

Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments
por: Pálinkás, Hajnalka L, et al.
Publicado: (2020)

FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment
por: Dimitrova, Emilia, et al.
Publicado: (2018)

Transposition-mediated DNA re-replication in maize
por: Zhang, Jianbo, et al.
Publicado: (2014)

Genetic dissection of the RNA polymerase II transcription cycle
por: Chou, Shao-Pei, et al.
Publicado: (2022)

Striking circadian neuron diversity and cycling of Drosophila alternative splicing
por: Wang, Qingqing, et al.
Publicado: (2018)

Prevalent and dynamic binding of the cell cycle checkpoint kinase Rad53 to gene promoters
por: Sheu, Yi-Jun, et al.
Publicado: (2022)

Caenorhabditis elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor
por: Giese, Gabrielle E, et al.
Publicado: (2020)

Amplification of a broad transcriptional program by a common factor triggers the meiotic cell cycle in mice
por: Kojima, Mina L, et al.
Publicado: (2019)

Cell cycle-specific loading of condensin I is regulated by the N-terminal tail of its kleisin subunit
por: Tane, Shoji, et al.
Publicado: (2022)

Proteins pinpoint double strand breaks
por: Cox, Michael M
Publicado: (2013)

The CDK-PLK1 axis targets the DNA damage checkpoint sensor protein RAD9 to promote cell proliferation and tolerance to genotoxic stress
por: Wakida, Takeshi, et al.
Publicado: (2017)

Conserved noncoding transcription and core promoter regulatory code in early Drosophila development
por: Batut, Philippe J, et al.
Publicado: (2017)

Telomere repeats induce domains of H3K27 methylation in Neurospora
por: Jamieson, Kirsty, et al.
Publicado: (2018)

Cis-regulatory evolution integrated the Bric-à-brac transcription factors into a novel fruit fly gene regulatory network
por: Roeske, Maxwell J, et al.
Publicado: (2018)

The genome of the Hi5 germ cell line from Trichoplusia ni, an agricultural pest and novel model for small RNA biology
por: Fu, Yu, et al.
Publicado: (2018)

High levels of histones promote whole-genome-duplications and trigger a Swe1(WEE1)-dependent phosphorylation of Cdc28(CDK1)
por: Maya Miles, Douglas, et al.
Publicado: (2018)

NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins
por: Campbell, Amy E, et al.
Publicado: (2018)

Codon choice directs constitutive mRNA levels in trypanosomes
por: de Freitas Nascimento, Janaina, et al.
Publicado: (2018)

MCM2–7-dependent cohesin loading during S phase promotes sister-chromatid cohesion
por: Zheng, Ge, et al.
Publicado: (2018)

Modulation of Prdm9-controlled meiotic chromosome asynapsis overrides hybrid sterility in mice
por: Gregorova, Sona, et al.
Publicado: (2018)

A gene-specific T2A-GAL4 library for Drosophila
por: Lee, Pei-Tseng, et al.
Publicado: (2018)

CRISPRi is not strand-specific at all loci and redefines the transcriptional landscape
por: Howe, Françoise S, et al.
Publicado: (2017)

A quantitative hypermorphic CNGC allele confers ectopic calcium flux and impairs cellular development
por: Chiasson, David M, et al.
Publicado: (2017)

Major transcriptional changes observed in the Fulani, an ethnic group less susceptible to malaria
por: Quin, Jaclyn E, et al.
Publicado: (2017)

Transcription of a 5’ extended mRNA isoform directs dynamic chromatin changes and interference of a downstream promoter
por: Chia, Minghao, et al.
Publicado: (2017)

Kinetochore inactivation by expression of a repressive mRNA
por: Chen, Jingxun, et al.
Publicado: (2017)

RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit
por: Milligan, Laura, et al.
Publicado: (2017)

Independent manipulation of histone H3 modifications in individual nucleosomes reveals the contributions of sister histones to transcription
por: Zhou, Zhen, et al.
Publicado: (2017)

Rapid DNA replication origin licensing protects stem cell pluripotency
por: Matson, Jacob Peter, et al.
Publicado: (2017)

A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis
por: Altemose, Nicolas, et al.
Publicado: (2017)

Efficient termination of nuclear lncRNA transcription promotes mitochondrial genome maintenance
por: du Mee, Dorine Jeanne Mariëtte, et al.
Publicado: (2018)

YTH-RNA-binding protein prevents deleterious expression of meiotic proteins by tethering their mRNAs to nuclear foci
por: Shichino, Yuichi, et al.
Publicado: (2018)

Multiple kinases inhibit origin licensing and helicase activation to ensure reductive cell division during meiosis
por: Phizicky, David V, et al.
Publicado: (2018)

Genome-wide mapping of sister chromatid exchange events in single yeast cells using Strand-seq
por: Claussin, Clémence, et al.
Publicado: (2017)

Convergence of topological domain boundaries, insulators, and polytene interbands revealed by high-resolution mapping of chromatin contacts in the early Drosophila melanogaster embryo
por: Stadler, Michael R, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_uoai35eho0au8e1c5acrf8qo0f