A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens

More than 100 million people have been infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Common laboratory mice are not susceptible to wild-type SARS-CoV-2 infection, challenging the development and testing of effective interventions. Here, we describe the development and t...

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Detalles Bibliográficos
Autores principales: Gary, Ebony N., Warner, Bryce M., Parzych, Elizabeth M., Griffin, Bryan D., Zhu, Xizhou, Tailor, Nikesh, Tursi, Nicholas J., Chan, Mable, Purwar, Mansi, Vendramelli, Robert, Choi, Jihae, Frost, Kathy L., Reeder, Sophia, Liaw, Kevin, Tello, Edgar, Ali, Ali R., Yun, Kun, Pei, Yanlong, Thomas, Sylvia P., Rghei, Amira D., Guilleman, Matthew M., Muthumani, Kar, Smith, Trevor, Wootton, Sarah K., Patel, Ami, Weiner, David B., Kobasa, Darwyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186956/
https://www.ncbi.nlm.nih.gov/pubmed/34124612
http://dx.doi.org/10.1016/j.isci.2021.102699

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