Cargando…
Gene Therapy for Overactive Bladder: A Review of BK-Channel α-Subunit Gene Transfer
A need exists for local (ie, bladder-specific) interventions to treat overactive bladder (OAB) with low risk of unwanted postprocedural outcomes. Gene therapy targeted to leverage endogenous physiology in bladder cells may assist in restoring normal cell and organ function. Herein, we review the pot...
Autores principales: | Andersson, Karl-Erik, Christ, George Joseph, Davies, Kelvin P, Rovner, Eric S, Melman, Arnold |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187094/ https://www.ncbi.nlm.nih.gov/pubmed/34113116 http://dx.doi.org/10.2147/TCRM.S291798 |
Ejemplares similares
-
Evaluating the safety and potential activity of URO‐902 (hMaxi‐K) gene transfer by intravesical instillation or direct injection into the bladder wall in female participants with idiopathic (non‐neurogenic) overactive bladder syndrome and detrusor overactivity from two double‐blind, imbalanced, placebo‐controlled randomized phase 1 trials
por: Rovner, Eric, et al.
Publicado: (2020) -
Attenuated BK channel function promotes overactive bladder in a rat model of obesity
por: Li, Ning, et al.
Publicado: (2019) -
Drugs for the overactive bladder: are there differences in persistence and compliance?
por: Andersson, Karl-Erik
Publicado: (2017) -
Drug therapy of overactive bladder - What is coming next?
por: Andersson, Karl-Erik
Publicado: (2015) -
Pharmacological consequences of the coexpression of BK channel α and auxiliary β subunits
por: Torres, Yolima P., et al.
Publicado: (2014)