Atypische Neuritis nervi optici (NNO): Bedeutung einer umfassenden Abklärung

A 65-year-old woman was referred for sudden bilateral loss of vision. She was vaccinated a few days earlier. The ophthalmological examination showed a massive optic disc swelling on both eyes. Magnetic resonance imaging (MRI) revealed suspected bilateral optic neuritis without cerebral involvement o...

Descripción completa

Detalles Bibliográficos
Autores principales: Yaïci, R., Carzoli, A., Bétis, F., Geerling, G., Guthoff, R., Guthoff, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2020
Materias:
Kasuistiken
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187178/
https://www.ncbi.nlm.nih.gov/pubmed/32705325
http://dx.doi.org/10.1007/s00347-020-01165-8
Descripción
Sumario:A 65-year-old woman was referred for sudden bilateral loss of vision. She was vaccinated a few days earlier. The ophthalmological examination showed a massive optic disc swelling on both eyes. Magnetic resonance imaging (MRI) revealed suspected bilateral optic neuritis without cerebral involvement or transverse myelitis. After serological detection of anti-MOG (myelin oligodendrocyte glycoprotein) antibodies, the patient was treated with high-dose corticosteroid pulse therapy until vision recovered. Discussion: an atypical optic neuritis may indicate a neuromyelitis optica spectrum disorder (NMOSD), which should be further characterized by determination of Aquaporin 4(AQP4)-IgG and MOG-IgG.

Ejemplares similares