Cargando…

Liver-targeting drugs and their effect on blood glucose and hepatic lipids

The global epidemic of non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) and the high prevalence among individuals with type 2 diabetes has attracted the attention of clinicians specialising in liver disorders. Many drugs are in the pipeline for the treatment of NAFLD/NASH, and se...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gastaldelli, Amalia, Stefan, Norbert, Häring, Hans-Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187191/ https://www.ncbi.nlm.nih.gov/pubmed/33877366 http://dx.doi.org/10.1007/s00125-021-05442-2

Ejemplares similares

Cholesterol Synthesis Is Associated with Hepatic Lipid Content and Dependent on Fructose/Glucose Intake in Healthy Humans
por: Silbernagel, Guenther, et al.
Publicado: (2012)

Glucose-Raising Polymorphisms in the Human Clock Gene Cryptochrome 2 (CRY2) Affect Hepatic Lipid Content
por: Machicao, Fausto, et al.
Publicado: (2016)

The Metabolically Benign and Malignant Fatty Liver
por: Stefan, Norbert, et al.
Publicado: (2011)

Gut-Pancreas-Liver Axis as a Target for Treatment of NAFLD/NASH
por: Svegliati-Baroni, Gianluca, et al.
Publicado: (2020)

Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogenesis
por: Hackl, Martina Theresa, et al.
Publicado: (2019)

Measuring and estimating insulin resistance in clinical and research settings
por: Gastaldelli, Amalia
Publicado: (2022)

Circulating Lysophosphatidylcholines Are Markers of a Metabolically Benign Nonalcoholic Fatty Liver
por: Lehmann, Rainer, et al.
Publicado: (2013)

From NASH to diabetes and from diabetes to NASH: Mechanisms and treatment options
por: Gastaldelli, Amalia, et al.
Publicado: (2019)

Metabolite Changes After Metabolic Surgery – Associations to Parameters Reflecting Glucose Homeostasis and Lipid Levels
por: Ahlin, Sofie, et al.
Publicado: (2021)

Improving glucose and lipids metabolism: drug development based on bile acid related targets
por: Shen, Hanchen, et al.
Publicado: (2021)

Diet and Exercise in the Treatment of Fatty Liver
por: Magkos, Faidon, et al.
Publicado: (2012)

Diabetes and Nonalcoholic Fatty Liver Disease
por: Kantartzis, Konstantinos, et al.
Publicado: (2012)

The Effects of Ecstasy on Liver Function Tests, Blood Glucose, and Lipids Profile of Male Rats
por: Shahraki, Mohammad Reza, et al.
Publicado: (2014)

Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease
por: Baumeier, Christian, et al.
Publicado: (2017)

201 Effects of GLP-1 on Glucose and Islet-Cell Secretory Responses to Protein Ingestion After Gastric Bypass or Sleeve Gastrectomy
por: Rayas, Maria S., et al.
Publicado: (2022)

The effects of medicinal and food homologous substances on blood lipid and blood glucose levels and liver function in patients with nonalcoholic fatty liver disease: a systematic review of randomized controlled trials
por: Zhang, Qian, et al.
Publicado: (2023)

Liver Enzymes Are Associated With Hepatic Insulin Resistance, Insulin Secretion, and Glucagon Concentration in Healthy Men and Women
por: Bonnet, Fabrice, et al.
Publicado: (2011)

Glucose-Raising Genetic Variants in MADD and ADCY5 Impair Conversion of Proinsulin to Insulin
por: Wagner, Robert, et al.
Publicado: (2011)

Non-Alcoholic Fatty Liver Disease (NAFLD) and Its Connection with Insulin Resistance, Dyslipidemia, Atherosclerosis and Coronary Heart Disease
por: Gaggini, Melania, et al.
Publicado: (2013)

Untangling the interplay of genetic and metabolic influences on beta-cell function: Examples of potential therapeutic implications involving TCF7L2 and FFAR1()
por: Wagner, Robert, et al.
Publicado: (2014)

Pathophysiology of Non Alcoholic Fatty Liver Disease
por: Petta, Salvatore, et al.
Publicado: (2016)

Unusual high blood glucose in ketoacidosis as first presentation of type 1 diabetes mellitus
por: Hörber, Sebastian, et al.
Publicado: (2018)

Homeostasis of Glucose and Lipid in Non-Alcoholic Fatty Liver Disease
por: Chao, Hsu-Wen, et al.
Publicado: (2019)

Regulation of Liver Glucose and Lipid Metabolism by Transcriptional Factors and Coactivators
por: Ramatchandirin, Balamurugan, et al.
Publicado: (2023)

Dysregulation of Lipid and Glucose Metabolism in Nonalcoholic Fatty Liver Disease
por: Bhat, Neha, et al.
Publicado: (2023)

Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice
por: Nuñez‐Durán, Esther, et al.
Publicado: (2017)

Comparison of Liver Fat Indices for the Diagnosis of Hepatic Steatosis and Insulin Resistance
por: Kahl, Sabine, et al.
Publicado: (2014)

Editorial: Hepatic glucose and lipid metabolism
por: Zhang, Huabing, et al.
Publicado: (2022)

Association of serum lipids with β-cell function in obese children and adolescents
por: Bedogni, Giorgio, et al.
Publicado: (2019)

Effect of Oral Sebacic Acid on Postprandial Glycemia, Insulinemia, and Glucose Rate of Appearance in Type 2 Diabetes
por: Iaconelli, Amerigo, et al.
Publicado: (2010)

Common variation in the sodium/glucose cotransporter 2 gene SLC5A2 does neither affect fasting nor glucose-suppressed plasma glucagon concentrations
por: Ordelheide, Anna-Maria, et al.
Publicado: (2017)

Allele Summation of Diabetes Risk Genes Predicts Impaired Glucose Tolerance in Female and Obese Individuals
por: Linder, Katarzyna, et al.
Publicado: (2012)

Effect of vigorous physical activity on blood lipid and glucose
por: Kwon, Hyoung-Jeong, et al.
Publicado: (2017)

Probing Hepatic Glucose Metabolism via (13)C NMR Spectroscopy in Perfused Livers—Applications to Drug Development
por: Miller, Corin O., et al.
Publicado: (2021)

Fat Mass and Obesity Associated (FTO) Gene and Hepatic Glucose and Lipid Metabolism
por: Mizuno, Tooru M.
Publicado: (2018)

Fatty Liver Index (FLI) Identifies Not Only Individuals with Liver Steatosis but Also at High Cardiometabolic Risk
por: Carli, Fabrizia, et al.
Publicado: (2023)

The Subtle Balance between Lipolysis and Lipogenesis: A Critical Point in Metabolic Homeostasis
por: Saponaro, Chiara, et al.
Publicado: (2015)

DPP4 gene variation affects GLP-1 secretion, insulin secretion, and glucose tolerance in humans with high body adiposity
por: Böhm, Anja, et al.
Publicado: (2017)

Novel phenotypes of prediabetes?
por: Häring, Hans-Ulrich
Publicado: (2016)

Effects of sitagliptin on ectopic fat contents and glucose metabolism in type 2 diabetic patients with fatty liver: A pilot study
por: Watanabe, Takahiro, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_m4k4fiabohfthsjvuei0gm61g4