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The oxidation and hypoglycaemic effect of sorafenib in streptozotocin-induced diabetic rats

BACKGROUND: Diabetes reduces the activity of CYP3A4 and may increase the exposure for the drugs metabolized by the isoenzyme. Sorafenib is a multi-targeted tyrosine kinase inhibitor (TKI), used for the treatment of advanced renal cell carcinoma, hepatocellular carcinoma and radioactive iodine resist...

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Detalles Bibliográficos
Autores principales:	Karbownik, Agnieszka, Stachowiak, Anna, Urjasz, Hanna, Sobańska, Katarzyna, Szczecińska, Agnieszka, Grabowski, Tomasz, Stanisławiak-Rudowicz, Joanna, Wolc, Anna, Grześkowiak, Edmund, Szałek, Edyta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187206/ https://www.ncbi.nlm.nih.gov/pubmed/32016844 http://dx.doi.org/10.1007/s43440-019-00021-0

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