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Decoding empagliflozin’s molecular mechanism of action in heart failure with preserved ejection fraction using artificial intelligence
The use of sodium-glucose co-transporter 2 inhibitors to treat heart failure with preserved ejection fraction (HFpEF) is under investigation in ongoing clinical trials, but the exact mechanism of action is unclear. Here we aimed to use artificial intelligence (AI) to characterize the mechanism of ac...
Autores principales: | Bayes-Genis, Antoni, Iborra-Egea, Oriol, Spitaleri, Giosafat, Domingo, Mar, Revuelta-López, Elena, Codina, Pau, Cediel, Germán, Santiago-Vacas, Evelyn, Cserkóová, Adriana, Pascual-Figal, Domingo, Núñez, Julio, Lupón, Josep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187349/ https://www.ncbi.nlm.nih.gov/pubmed/34103605 http://dx.doi.org/10.1038/s41598-021-91546-z |
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