Systematic benchmarking of tools for CpG methylation detection from nanopore sequencing

DNA methylation plays a fundamental role in the control of gene expression and genome integrity. Although there are multiple tools that enable its detection from Nanopore sequencing, their accuracy remains largely unknown. Here, we present a systematic benchmarking of tools for the detection of CpG...

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Detalles Bibliográficos
Autores principales: Yuen, Zaka Wing-Sze, Srivastava, Akanksha, Daniel, Runa, McNevin, Dennis, Jack, Cameron, Eyras, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187371/
https://www.ncbi.nlm.nih.gov/pubmed/34103501
http://dx.doi.org/10.1038/s41467-021-23778-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187371/
https://www.ncbi.nlm.nih.gov/pubmed/34103501
http://dx.doi.org/10.1038/s41467-021-23778-6

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