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Systematic benchmarking of tools for CpG methylation detection from nanopore sequencing
DNA methylation plays a fundamental role in the control of gene expression and genome integrity. Although there are multiple tools that enable its detection from Nanopore sequencing, their accuracy remains largely unknown. Here, we present a systematic benchmarking of tools for the detection of CpG...
Autores principales: | Yuen, Zaka Wing-Sze, Srivastava, Akanksha, Daniel, Runa, McNevin, Dennis, Jack, Cameron, Eyras, Eduardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187371/ https://www.ncbi.nlm.nih.gov/pubmed/34103501 http://dx.doi.org/10.1038/s41467-021-23778-6 |
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