Dynamics of replication origin over-activation

Safeguards against excess DNA replication are often dysregulated in cancer, and driving cancer cells towards over-replication is a promising therapeutic strategy. We determined DNA synthesis patterns in cancer cells undergoing partial genome re-replication due to perturbed regulatory interactions (r...

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Detalles Bibliográficos
Autores principales: Fu, Haiqing, Redon, Christophe E., Thakur, Bhushan L., Utani, Koichi, Sebastian, Robin, Jang, Sang-Min, Gross, Jacob M., Mosavarpour, Sara, Marks, Anna B., Zhuang, Sophie Z., Lazar, Sarah B., Rao, Mishal, Mencer, Shira T., Baris, Adrian M., Pongor, Lorinc S., Aladjem, Mirit I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187443/
https://www.ncbi.nlm.nih.gov/pubmed/34103496
http://dx.doi.org/10.1038/s41467-021-23835-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187443/
https://www.ncbi.nlm.nih.gov/pubmed/34103496
http://dx.doi.org/10.1038/s41467-021-23835-0

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