Role of noncoding RNA in drug resistance of prostate cancer

Prostate cancer is one of the most prevalent forms of cancer around the world. Androgen-deprivation treatment and chemotherapy are the curative approaches used to suppress prostate cancer progression. However, drug resistance is extensively and hard to overcome even though remarkable progress has be...

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Autores principales: Ding, Lifeng, Wang, Ruyue, Shen, Danyang, Cheng, Sheng, Wang, Huan, Lu, Zeyi, Zheng, Qiming, Wang, Liya, Xia, Liqun, Li, Gonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187453/
https://www.ncbi.nlm.nih.gov/pubmed/34103477
http://dx.doi.org/10.1038/s41419-021-03854-x
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author Ding, Lifeng
Wang, Ruyue
Shen, Danyang
Cheng, Sheng
Wang, Huan
Lu, Zeyi
Zheng, Qiming
Wang, Liya
Xia, Liqun
Li, Gonghui
author_facet Ding, Lifeng
Wang, Ruyue
Shen, Danyang
Cheng, Sheng
Wang, Huan
Lu, Zeyi
Zheng, Qiming
Wang, Liya
Xia, Liqun
Li, Gonghui
author_sort Ding, Lifeng
collection PubMed
description Prostate cancer is one of the most prevalent forms of cancer around the world. Androgen-deprivation treatment and chemotherapy are the curative approaches used to suppress prostate cancer progression. However, drug resistance is extensively and hard to overcome even though remarkable progress has been made in recent decades. Noncoding RNAs, such as miRNAs, lncRNAs, and circRNAs, are a group of cellular RNAs which participate in various cellular processes and diseases. Recently, accumulating evidence has highlighted the vital role of non-coding RNA in the development of drug resistance in prostate cancer. In this review, we summarize the important roles of these three classes of noncoding RNA in drug resistance and the potential therapeutic applications in this disease.
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spelling pubmed-81874532021-06-28 Role of noncoding RNA in drug resistance of prostate cancer Ding, Lifeng Wang, Ruyue Shen, Danyang Cheng, Sheng Wang, Huan Lu, Zeyi Zheng, Qiming Wang, Liya Xia, Liqun Li, Gonghui Cell Death Dis Review Article Prostate cancer is one of the most prevalent forms of cancer around the world. Androgen-deprivation treatment and chemotherapy are the curative approaches used to suppress prostate cancer progression. However, drug resistance is extensively and hard to overcome even though remarkable progress has been made in recent decades. Noncoding RNAs, such as miRNAs, lncRNAs, and circRNAs, are a group of cellular RNAs which participate in various cellular processes and diseases. Recently, accumulating evidence has highlighted the vital role of non-coding RNA in the development of drug resistance in prostate cancer. In this review, we summarize the important roles of these three classes of noncoding RNA in drug resistance and the potential therapeutic applications in this disease. Nature Publishing Group UK 2021-06-08 /pmc/articles/PMC8187453/ /pubmed/34103477 http://dx.doi.org/10.1038/s41419-021-03854-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Ding, Lifeng
Wang, Ruyue
Shen, Danyang
Cheng, Sheng
Wang, Huan
Lu, Zeyi
Zheng, Qiming
Wang, Liya
Xia, Liqun
Li, Gonghui
Role of noncoding RNA in drug resistance of prostate cancer
title Role of noncoding RNA in drug resistance of prostate cancer
title_full Role of noncoding RNA in drug resistance of prostate cancer
title_fullStr Role of noncoding RNA in drug resistance of prostate cancer
title_full_unstemmed Role of noncoding RNA in drug resistance of prostate cancer
title_short Role of noncoding RNA in drug resistance of prostate cancer
title_sort role of noncoding rna in drug resistance of prostate cancer
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187453/
https://www.ncbi.nlm.nih.gov/pubmed/34103477
http://dx.doi.org/10.1038/s41419-021-03854-x
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