Increasing the Ascomycin Yield by Relieving the Inhibition of Acetyl/Propionyl-CoA Carboxylase by the Signal Transduction Protein GlnB

Ascomycin (FK520) is a multifunctional antibiotic produced by Streptomyces hygroscopicus var. ascomyceticus. In this study, we demonstrated that the inactivation of GlnB, a signal transduction protein belonging to the PII family, can increase the production of ascomycin by strengthening the supply o...

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Detalles Bibliográficos
Autores principales: Wang, Pan, Wang, Xin, Yin, Ying, He, Mingliang, Tan, Wei, Gao, Wenting, Wen, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187598/
https://www.ncbi.nlm.nih.gov/pubmed/34122395
http://dx.doi.org/10.3389/fmicb.2021.684193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187598/
https://www.ncbi.nlm.nih.gov/pubmed/34122395
http://dx.doi.org/10.3389/fmicb.2021.684193

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