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Peganum harmala enhanced GLP-1 and restored insulin signaling to alleviate AlCl(3)-induced Alzheimer-like pathology model

Peganum harmala (P. harmala) is a folk medicinal herb used in the Sinai Peninsula (Egypt) as a remedy for central disorders. The main constituents, harmine and harmaline, have displayed therapeutic efficacy against Alzheimer’s disease (AD); however, the P. harmala potential on sensitizing central in...

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Detalles Bibliográficos
Autores principales: Saleh, Rofida A., Eissa, Tarek F., Abdallah, Dalaal M., Saad, Muhammed A., El-Abhar, Hanan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187628/
https://www.ncbi.nlm.nih.gov/pubmed/34103557
http://dx.doi.org/10.1038/s41598-021-90545-4