Cargando…

Toxoplasma gondii Type-I ROP18 Targeting Human E3 Ligase TRIM21 for Immune Escape

Toxoplasma gondii is an intracellular pathogen that exerts its virulence through inhibiting host’s innate immune responses, which is mainly related to the type II interferon (IFN-γ) response. IFN-γ inducible tripartite motif 21 (TRIM21), an E3 ligase, plays an important role in anti-infection respon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yao, Lijie, Xu, Liqing, Zhou, Lijuan, Wu, Shuizhen, Zou, Weihao, Chen, Min, Chen, Jiating, Peng, Hongjuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187923/ https://www.ncbi.nlm.nih.gov/pubmed/34124071 http://dx.doi.org/10.3389/fcell.2021.685913

Ejemplares similares

Toxoplasma gondii gra5 deletion mutant protects hosts against Toxoplasma gondii infection and breast tumors
por: Chen, Min, et al.
Publicado: (2023)

Host Cell Vimentin Restrains Toxoplasma gondii Invasion and Phosphorylation of Vimentin is Partially Regulated by Interaction with TgROP18
por: He, Cheng, et al.
Publicado: (2017)

The Polymorphic Pseudokinase ROP5 Controls Virulence in Toxoplasma gondii by Regulating the Active Kinase ROP18
por: Behnke, Michael S., et al.
Publicado: (2012)

TgROP18 targets IL20RB for host-defense-related-STAT3 activation during Toxoplasma gondii infection
por: Kong, Ling, et al.
Publicado: (2020)

Characterization of Cytosine Methylation and the DNA Methyltransferases of Toxoplasma gondii
por: Wei, Haixia, et al.
Publicado: (2017)

ROP18 Is a Rhoptry Kinase Controlling the Intracellular Proliferation of Toxoplasma gondii
por: El Hajj, Hiba, et al.
Publicado: (2007)

Protein targets of thiazolidinone derivatives in Toxoplasma gondii and insights into their binding to ROP18
por: Molina, Diego, et al.
Publicado: (2018)

Immune Protection of Rhoptry Protein 21 (ROP21) of Toxoplasma gondii as a DNA Vaccine Against Toxoplasmosis
por: Zhang, Zhenchao, et al.
Publicado: (2018)

Expression and Purification of Recombinant ROP1 of Toxoplasma gondii in Bacteria
por: Mohabati, Reyhaneh, et al.
Publicado: (2013)

The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response
por: Niedelman, Wendy, et al.
Publicado: (2012)

Toxoplasma gondii Superinfection and Virulence during Secondary Infection Correlate with the Exact ROP5/ROP18 Allelic Combination
por: Jensen, Kirk D. C., et al.
Publicado: (2015)

Toxoplasma gondii infection possibly reverses host immunosuppression to restrain tumor growth
por: Chen, Jiating, et al.
Publicado: (2022)

Prediction of Toxoplasma gondii virulence factor ROP18 competitive inhibitors by virtual screening
por: Yin, Kun, et al.
Publicado: (2019)

Anti-infection roles of miR-155-5p packaged in exosomes secreted by dendritic cells infected with Toxoplasma gondii
por: Jiang, Dan, et al.
Publicado: (2022)

Influenza Virus-Like Particles Presenting both Toxoplasma gondii ROP4 and ROP13 Enhance Protection against T. gondii Infection
por: Kang, Hae-Ji, et al.
Publicado: (2019)

Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii
por: Behnke, Michael S., et al.
Publicado: (2015)

Adjuvantic cytokine IL-33 improves the protective immunity of cocktailed DNA vaccine of ROP5 and ROP18 against toxoplasma gondii infection in mice
por: Zhu, Yu-Chao, et al.
Publicado: (2020)

ROP18-Mediated Transcriptional Reprogramming of HEK293T Cell Reveals New Roles of ROP18 in the Interplay Between Toxoplasma gondii and the Host Cell
por: Li, Jie-Xi, et al.
Publicado: (2020)

Detection of Toxoplasma gondii Infections using Virus-Like Particles Displaying T. gondii ROP4 Antigen
por: Kim, Min-Ju, et al.
Publicado: (2021)

ATF6β is a host cellular target of the Toxoplasma gondii virulence factor ROP18
por: Yamamoto, Masahiro, et al.
Publicado: (2011)

ROP18 Is a Key Factor Responsible for Virulence Difference between Toxoplasma gondii and Neospora caninum
por: Lei, Tao, et al.
Publicado: (2014)

The Toxoplasma gondii virulence factor ROP16 acts in cis and trans, and suppresses T cell responses
por: Chen, Longfei, et al.
Publicado: (2020)

In vitro Anti-parasitic Activity of Pelargonium X. asperum Essential Oil Against Toxoplasma gondii
por: Huang, Si-Yang, et al.
Publicado: (2021)

TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles
por: Foltz, Clémence, et al.
Publicado: (2017)

Epitope analysis and protection by a ROP19 DNA vaccine against Toxoplasma gondii
por: Zhou, Jian, et al.
Publicado: (2016)

Screening and Identification of the Host Proteins Interacting with Toxoplasma gondii Rhoptry Protein ROP16
por: Pan, Ming, et al.
Publicado: (2017)

Efficient Cholesterol Transport in Dendritic Cells Defines Optimal Exogenous Antigen Presentation and Toxoplasma gondii Proliferation
por: Croce, Cristina, et al.
Publicado: (2022)

Licarin-B Exhibits Activity Against the Toxoplasma gondii RH Strain by Damaging Mitochondria and Activating Autophagy
por: Zhang, Jili, et al.
Publicado: (2021)

Influence of Two Major Toxoplasma Gondii Virulence Factors (ROP16 and ROP18) on the Immune Response of Peripheral Blood Mononuclear Cells to Human Toxoplasmosis Infection
por: Hernández-de-los-Ríos, Alejandro, et al.
Publicado: (2019)

Protective efficacy of recombinant canine adenovirus type-2 expressing TgROP18 (CAV-2-ROP18) against acute and chronic Toxoplasma gondii infection in mice
por: Li, Xiu-Zhen, et al.
Publicado: (2015)

Functional Characterization of 17 Protein Serine/Threonine Phosphatases in Toxoplasma gondii Using CRISPR-Cas9 System
por: Liang, Qin-Li, et al.
Publicado: (2022)

The Toxoplasma gondii protein ROP2 mediates host organelle association with the parasitophorous vacuole membrane
por: Sinai, Anthony P., et al.
Publicado: (2001)

The Rhoptry Pseudokinase ROP54 Modulates Toxoplasma gondii Virulence and Host GBP2 Loading
por: Kim, Elliot W., et al.
Publicado: (2016)

Differential Impacts on Host Transcription by ROP and GRA Effectors from the Intracellular Parasite Toxoplasma gondii
por: Rastogi, Suchita, et al.
Publicado: (2020)

Toxoplasma gondii ROP16(I) Deletion: The Exacerbated Impact on Adverse Pregnant Outcomes in Mice
por: Cui, Wen, et al.
Publicado: (2020)

The secreted kinase ROP17 promotes Toxoplasma gondii dissemination by hijacking monocyte tissue migration
por: Drewry, Lisa L, et al.
Publicado: (2019)

ROP39 is an Irgb10-specific parasite effector that modulates acute Toxoplasma gondii virulence
por: Singh, Shishir, et al.
Publicado: (2023)

Recent Advances in the Roles of Autophagy and Autophagy Proteins in Host Cells During Toxoplasma gondii Infection and Potential Therapeutic Implications
por: Subauste, Carlos S.
Publicado: (2021)

A mechanistic study of Toxoplasma gondii ROP18 inhibiting differentiation of C17.2 neural stem cells
por: Zhang, Xian, et al.
Publicado: (2017)

The Dual Roles of MAGE-C2 in p53 Ubiquitination and Cell Proliferation Through E3 Ligases MDM2 and TRIM28
por: Liu, Yunshan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6gq4hiv48fk0u6crn8l6gt8mmm