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Dysglycemia in Critically Ill Children Admitted to Jimma Medical Centre, Southwest Ethiopia

BACKGROUND: Abnormal blood glucose level is one of the most frequently encountered problems in children with severe illnesses. However, its magnitude and outcome have rarely been determined in Ethiopia. We aimed to determine the magnitude, associated factors and outcome of dysglycemia in critically...

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Autores principales: Sime, Habtamu, Berhane, Melkamu, Tilahun, Tsion, Kedir, Temam, Dereje, Diriba, Beshir, Muktar, Tadesse, Iyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research and Publications Office of Jimma University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188083/
https://www.ncbi.nlm.nih.gov/pubmed/34158783
http://dx.doi.org/10.4314/ejhs.v31i2.14
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author Sime, Habtamu
Berhane, Melkamu
Tilahun, Tsion
Kedir, Temam
Dereje, Diriba
Beshir, Muktar
Tadesse, Iyasu
author_facet Sime, Habtamu
Berhane, Melkamu
Tilahun, Tsion
Kedir, Temam
Dereje, Diriba
Beshir, Muktar
Tadesse, Iyasu
author_sort Sime, Habtamu
collection PubMed
description BACKGROUND: Abnormal blood glucose level is one of the most frequently encountered problems in children with severe illnesses. However, its magnitude and outcome have rarely been determined in Ethiopia. We aimed to determine the magnitude, associated factors and outcome of dysglycemia in critically ill children admitted to Jimma Medical Center. METHODS: Prospective longitudinal study was conducted on children aged 28 days to 14 years admitted with critical illnesses at the different units of the Department of Pediatrics and Child Health of Jimma Medical Center, Southwest Ethiopia, from June to August 2019. Data were collected by trained medical personnel using structured questionnaire and analyzed using Statistical Package for Social Sciences (SPSS) windows version 20.0. Dysglycemia was considered whenever the child had a random blood sugar >150mg/dl or <45mg/dl. RESULT: Dysglycemia was seen at admission in 139/481, 28.9% children; 24 (5.0%) had hypoglycemia whereas 115 (23.9%) had hyperglycemia. The factors associated with dysglycemia at admission were severe acute malnutrition (p=002, AOR=3.09, CI=1.18,7.77), impaired mental status (p=0.003, AOR=4.63, CI=1.68, 12.71), place of residence (p=0.01, AOR=1.85, CI=1.15–2.96) and presence of diarrhea on date of admission. Among the children who had dysglycemia at admission, 16/139, 11.5% died. CONCLUSION: Dysglycemia is a common problem in critically ill children in the setting. Blood glucose level should be determined for all critically ill children, and routine empirical administration of dextrose should be minimized since most of the children with dysglycemia had hyperglycemia than hypoglycemia.
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spelling pubmed-81880832021-06-21 Dysglycemia in Critically Ill Children Admitted to Jimma Medical Centre, Southwest Ethiopia Sime, Habtamu Berhane, Melkamu Tilahun, Tsion Kedir, Temam Dereje, Diriba Beshir, Muktar Tadesse, Iyasu Ethiop J Health Sci Original Article BACKGROUND: Abnormal blood glucose level is one of the most frequently encountered problems in children with severe illnesses. However, its magnitude and outcome have rarely been determined in Ethiopia. We aimed to determine the magnitude, associated factors and outcome of dysglycemia in critically ill children admitted to Jimma Medical Center. METHODS: Prospective longitudinal study was conducted on children aged 28 days to 14 years admitted with critical illnesses at the different units of the Department of Pediatrics and Child Health of Jimma Medical Center, Southwest Ethiopia, from June to August 2019. Data were collected by trained medical personnel using structured questionnaire and analyzed using Statistical Package for Social Sciences (SPSS) windows version 20.0. Dysglycemia was considered whenever the child had a random blood sugar >150mg/dl or <45mg/dl. RESULT: Dysglycemia was seen at admission in 139/481, 28.9% children; 24 (5.0%) had hypoglycemia whereas 115 (23.9%) had hyperglycemia. The factors associated with dysglycemia at admission were severe acute malnutrition (p=002, AOR=3.09, CI=1.18,7.77), impaired mental status (p=0.003, AOR=4.63, CI=1.68, 12.71), place of residence (p=0.01, AOR=1.85, CI=1.15–2.96) and presence of diarrhea on date of admission. Among the children who had dysglycemia at admission, 16/139, 11.5% died. CONCLUSION: Dysglycemia is a common problem in critically ill children in the setting. Blood glucose level should be determined for all critically ill children, and routine empirical administration of dextrose should be minimized since most of the children with dysglycemia had hyperglycemia than hypoglycemia. Research and Publications Office of Jimma University 2021-03 /pmc/articles/PMC8188083/ /pubmed/34158783 http://dx.doi.org/10.4314/ejhs.v31i2.14 Text en © 2021 Habtamu Sime, et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Original Article
Sime, Habtamu
Berhane, Melkamu
Tilahun, Tsion
Kedir, Temam
Dereje, Diriba
Beshir, Muktar
Tadesse, Iyasu
Dysglycemia in Critically Ill Children Admitted to Jimma Medical Centre, Southwest Ethiopia
title Dysglycemia in Critically Ill Children Admitted to Jimma Medical Centre, Southwest Ethiopia
title_full Dysglycemia in Critically Ill Children Admitted to Jimma Medical Centre, Southwest Ethiopia
title_fullStr Dysglycemia in Critically Ill Children Admitted to Jimma Medical Centre, Southwest Ethiopia
title_full_unstemmed Dysglycemia in Critically Ill Children Admitted to Jimma Medical Centre, Southwest Ethiopia
title_short Dysglycemia in Critically Ill Children Admitted to Jimma Medical Centre, Southwest Ethiopia
title_sort dysglycemia in critically ill children admitted to jimma medical centre, southwest ethiopia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188083/
https://www.ncbi.nlm.nih.gov/pubmed/34158783
http://dx.doi.org/10.4314/ejhs.v31i2.14
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