Hypermethylation of Hepatic Mitochondrial ND6 Provokes Systemic Insulin Resistance

Mitochondrial epigenetics is rising as intriguing notion for its potential involvement in aging and diseases, while the details remain largely unexplored. Here it is shown that among the 13 mitochondrial DNA (mtDNA) encoded genes, NADH‐dehydrogenase 6 (ND6) transcript is primarily decreased in obese...

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Detalles Bibliográficos
Autores principales: Cao, Ke, Lv, Weiqiang, Wang, Xueqiang, Dong, Shanshan, Liu, Xuyun, Yang, Tielin, Xu, Jie, Zeng, Mengqi, Zou, Xuan, Zhao, Daina, Ma, Qingqing, Lin, Mu, Long, Jiangang, Zang, Weijin, Gao, Feng, Feng, Zhihui, Liu, Jiankang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188198/
https://www.ncbi.nlm.nih.gov/pubmed/34141522
http://dx.doi.org/10.1002/advs.202004507

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