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Is spinal tuberculosis changing with changing time?

INTRODUCTION: Spinal tuberculosis is a chronic destructive disease with long-term morbidity. Patients are usually young especially from a poor socioeconomic background. Destruction of the intervertebral disk space and the adjacent vertebral bodies is the characteristic lesion. The dorsal spine is th...

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Autores principales: Hasan Khan, Mohammad Noah, Jamal, Abdul Basit, Hafeez, Auzair, Sadiq, Marium, Rasool, Muhammad Umer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188246/
https://www.ncbi.nlm.nih.gov/pubmed/34141411
http://dx.doi.org/10.1016/j.amsu.2021.102421
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author Hasan Khan, Mohammad Noah
Jamal, Abdul Basit
Hafeez, Auzair
Sadiq, Marium
Rasool, Muhammad Umer
author_facet Hasan Khan, Mohammad Noah
Jamal, Abdul Basit
Hafeez, Auzair
Sadiq, Marium
Rasool, Muhammad Umer
author_sort Hasan Khan, Mohammad Noah
collection PubMed
description INTRODUCTION: Spinal tuberculosis is a chronic destructive disease with long-term morbidity. Patients are usually young especially from a poor socioeconomic background. Destruction of the intervertebral disk space and the adjacent vertebral bodies is the characteristic lesion. The dorsal spine is the most affected region with multi-level noncontiguous involvement being detected more frequently. Patients usually present with chronic back pain associated with spinal tenderness, paraplegia, spinal deformities, as well as with constitutional symptoms. Magnetic resonance imaging has proved to be more sensitive and specific for its diagnosis, but availability and affordability of this investigation remain a problem in developing countries. Anti-tuberculous drug therapy has revolutionized the treatment of this debilitating disease. Surgery is still required in selected cases especially with evolving neurological deficit, progressive deformity, intractable pain and lack of response to drug therapy. With early diagnosis and effective treatment, prognosis is generally good. Materials/Methods: After getting permission from the clinical governance department, We collected the retrospective data of 305 patients with diagnosed spinal tuberculosis, who underwent surgical intervention. RESULTS: There was no significant difference in incidence among males and females. Housewives were the most affected. Lower dorsal spinal was the commonest site involved but our study didn't confirm the incidence of multi-level disease process. Anterior decompression along with Cage fixation was most frequently performed procedure. CONCLUSION: Despite the availability of highly effective antituberculous drugs, advanced surgical procedure, the spinal tuberculosis still maintains its demographic profile. There has been no change in characteristics of spinal presentation of this chronic debilitating disease. Patients continue to suffer the same way as they were suffering decades ago.
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spelling pubmed-81882462021-06-16 Is spinal tuberculosis changing with changing time? Hasan Khan, Mohammad Noah Jamal, Abdul Basit Hafeez, Auzair Sadiq, Marium Rasool, Muhammad Umer Ann Med Surg (Lond) Review INTRODUCTION: Spinal tuberculosis is a chronic destructive disease with long-term morbidity. Patients are usually young especially from a poor socioeconomic background. Destruction of the intervertebral disk space and the adjacent vertebral bodies is the characteristic lesion. The dorsal spine is the most affected region with multi-level noncontiguous involvement being detected more frequently. Patients usually present with chronic back pain associated with spinal tenderness, paraplegia, spinal deformities, as well as with constitutional symptoms. Magnetic resonance imaging has proved to be more sensitive and specific for its diagnosis, but availability and affordability of this investigation remain a problem in developing countries. Anti-tuberculous drug therapy has revolutionized the treatment of this debilitating disease. Surgery is still required in selected cases especially with evolving neurological deficit, progressive deformity, intractable pain and lack of response to drug therapy. With early diagnosis and effective treatment, prognosis is generally good. Materials/Methods: After getting permission from the clinical governance department, We collected the retrospective data of 305 patients with diagnosed spinal tuberculosis, who underwent surgical intervention. RESULTS: There was no significant difference in incidence among males and females. Housewives were the most affected. Lower dorsal spinal was the commonest site involved but our study didn't confirm the incidence of multi-level disease process. Anterior decompression along with Cage fixation was most frequently performed procedure. CONCLUSION: Despite the availability of highly effective antituberculous drugs, advanced surgical procedure, the spinal tuberculosis still maintains its demographic profile. There has been no change in characteristics of spinal presentation of this chronic debilitating disease. Patients continue to suffer the same way as they were suffering decades ago. Elsevier 2021-05-28 /pmc/articles/PMC8188246/ /pubmed/34141411 http://dx.doi.org/10.1016/j.amsu.2021.102421 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Hasan Khan, Mohammad Noah
Jamal, Abdul Basit
Hafeez, Auzair
Sadiq, Marium
Rasool, Muhammad Umer
Is spinal tuberculosis changing with changing time?
title Is spinal tuberculosis changing with changing time?
title_full Is spinal tuberculosis changing with changing time?
title_fullStr Is spinal tuberculosis changing with changing time?
title_full_unstemmed Is spinal tuberculosis changing with changing time?
title_short Is spinal tuberculosis changing with changing time?
title_sort is spinal tuberculosis changing with changing time?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188246/
https://www.ncbi.nlm.nih.gov/pubmed/34141411
http://dx.doi.org/10.1016/j.amsu.2021.102421
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