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Protein purification and crystallization of HLA-A∗02:01 in complex with SARS-CoV-2 peptides

Understanding T-cell responses requires identifying viral peptides presented by human leukocyte antigens (HLAs). X-ray crystallography can be used to visualize their presentation. This protocol describes the expression, purification, and crystallization of HLA-A∗02:01, one of the most frequent HLA i...

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Detalles Bibliográficos
Autores principales:	Chatzileontiadou, Demetra S.M., Szeto, Christopher, Jayasinghe, Dhilshan, Gras, Stephanie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188458/ https://www.ncbi.nlm.nih.gov/pubmed/34124695 http://dx.doi.org/10.1016/j.xpro.2021.100635

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