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Controllable stereoinversion in DNA-catalyzed olefin cyclopropanation via cofactor modification

The assembly of DNA with metal-complex cofactors can form promising biocatalysts for asymmetric reactions, although catalytic performance is typically limited by low enantioselectivities and stereo-control remains a challenge. Here, we engineer G-quadruplex-based DNA biocatalysts for an asymmetric c...

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Detalles Bibliográficos
Autores principales: Hao, Jingya, Miao, Wenhui, Lu, Shengmei, Cheng, Yu, Jia, Guoqing, Li, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188488/
https://www.ncbi.nlm.nih.gov/pubmed/34168845
http://dx.doi.org/10.1039/d1sc00755f