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Biomechanical Effects of a Cross Connector in Sacral Fractures – A Finite Element Analysis

Background: Spinopelvic fractures and approaches of operative stabilization have been a source of controversial discussion. Biomechanical data support the benefit of a spinopelvic stabilization and minimally invasive procedures help to reduce the dissatisfying complication rate. The role of a cross...

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Autores principales: Gierig, Meike, Liu, Fangrui, Weiser, Lukas, Lehmann, Wolfgang, Wriggers, Peter, Marino, Michele, Saul, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188498/
https://www.ncbi.nlm.nih.gov/pubmed/34124023
http://dx.doi.org/10.3389/fbioe.2021.669321
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author Gierig, Meike
Liu, Fangrui
Weiser, Lukas
Lehmann, Wolfgang
Wriggers, Peter
Marino, Michele
Saul, Dominik
author_facet Gierig, Meike
Liu, Fangrui
Weiser, Lukas
Lehmann, Wolfgang
Wriggers, Peter
Marino, Michele
Saul, Dominik
author_sort Gierig, Meike
collection PubMed
description Background: Spinopelvic fractures and approaches of operative stabilization have been a source of controversial discussion. Biomechanical data support the benefit of a spinopelvic stabilization and minimally invasive procedures help to reduce the dissatisfying complication rate. The role of a cross connector within spinopelvic devices remains inconclusive. We aimed to analyze the effect of a cross connector in a finite element model (FE model). Study Design: A FE model of the L1-L5 spine segment with pelvis and a spinopelvic stabilization was reconstructed from patient-specific CT images. The biomechanical relevance of a cross connector in a Denis zone I (AO: 61-B2) sacrum fracture was assessed in the FE model by applying bending and twisting forces with and without a cross connector. Biomechanical outcomes from the numerical model were investigated also considering uncertainties in material properties and levels of osseointegration. Results: The designed FE model showed comparable values in range-of-motion (ROM) and stresses with reference to the literature. The superiority of the spinopelvic stabilization (L5/Os ilium) ± cross connector compared to a non-operative procedure was confirmed in all analyzed loading conditions by reduced ROM and principal stresses in the disk L5/S1, vertebral body L5 and the fracture area. By considering the combination of all loading cases, the presence of a cross connector reduced the maximum stresses in the fracture area of around 10%. This difference has been statistically validated (p < 0.0001). Conclusion: The implementation of a spinopelvic stabilization (L5/Os ilium) in sacrum fractures sustained the fracture and led to enhanced biomechanical properties compared to a non-reductive procedure. While the additional cross connector did not alter the resulting ROM in L4/L5 or L5/sacrum, the reduction of the maximum stresses in the fracture area was significant.
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spelling pubmed-81884982021-06-10 Biomechanical Effects of a Cross Connector in Sacral Fractures – A Finite Element Analysis Gierig, Meike Liu, Fangrui Weiser, Lukas Lehmann, Wolfgang Wriggers, Peter Marino, Michele Saul, Dominik Front Bioeng Biotechnol Bioengineering and Biotechnology Background: Spinopelvic fractures and approaches of operative stabilization have been a source of controversial discussion. Biomechanical data support the benefit of a spinopelvic stabilization and minimally invasive procedures help to reduce the dissatisfying complication rate. The role of a cross connector within spinopelvic devices remains inconclusive. We aimed to analyze the effect of a cross connector in a finite element model (FE model). Study Design: A FE model of the L1-L5 spine segment with pelvis and a spinopelvic stabilization was reconstructed from patient-specific CT images. The biomechanical relevance of a cross connector in a Denis zone I (AO: 61-B2) sacrum fracture was assessed in the FE model by applying bending and twisting forces with and without a cross connector. Biomechanical outcomes from the numerical model were investigated also considering uncertainties in material properties and levels of osseointegration. Results: The designed FE model showed comparable values in range-of-motion (ROM) and stresses with reference to the literature. The superiority of the spinopelvic stabilization (L5/Os ilium) ± cross connector compared to a non-operative procedure was confirmed in all analyzed loading conditions by reduced ROM and principal stresses in the disk L5/S1, vertebral body L5 and the fracture area. By considering the combination of all loading cases, the presence of a cross connector reduced the maximum stresses in the fracture area of around 10%. This difference has been statistically validated (p < 0.0001). Conclusion: The implementation of a spinopelvic stabilization (L5/Os ilium) in sacrum fractures sustained the fracture and led to enhanced biomechanical properties compared to a non-reductive procedure. While the additional cross connector did not alter the resulting ROM in L4/L5 or L5/sacrum, the reduction of the maximum stresses in the fracture area was significant. Frontiers Media S.A. 2021-05-26 /pmc/articles/PMC8188498/ /pubmed/34124023 http://dx.doi.org/10.3389/fbioe.2021.669321 Text en Copyright © 2021 Gierig, Liu, Weiser, Lehmann, Wriggers, Marino and Saul. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Gierig, Meike
Liu, Fangrui
Weiser, Lukas
Lehmann, Wolfgang
Wriggers, Peter
Marino, Michele
Saul, Dominik
Biomechanical Effects of a Cross Connector in Sacral Fractures – A Finite Element Analysis
title Biomechanical Effects of a Cross Connector in Sacral Fractures – A Finite Element Analysis
title_full Biomechanical Effects of a Cross Connector in Sacral Fractures – A Finite Element Analysis
title_fullStr Biomechanical Effects of a Cross Connector in Sacral Fractures – A Finite Element Analysis
title_full_unstemmed Biomechanical Effects of a Cross Connector in Sacral Fractures – A Finite Element Analysis
title_short Biomechanical Effects of a Cross Connector in Sacral Fractures – A Finite Element Analysis
title_sort biomechanical effects of a cross connector in sacral fractures – a finite element analysis
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188498/
https://www.ncbi.nlm.nih.gov/pubmed/34124023
http://dx.doi.org/10.3389/fbioe.2021.669321
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