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Pinhead antagonizes Admp to promote notochord formation

Dorsoventral patterning of a vertebrate embryo critically depends on the activity of Smad1 that mediates signaling by BMP proteins, anti-dorsalizing morphogenetic protein (Admp), and their antagonists. Pinhead (Pnhd), a cystine-knot-containing secreted protein, is expressed in the ventrolateral meso...

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Detalles Bibliográficos
Autores principales: Itoh, Keiji, Ossipova, Olga, Sokol, Sergei Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188501/
https://www.ncbi.nlm.nih.gov/pubmed/34142034
http://dx.doi.org/10.1016/j.isci.2021.102520

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