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Individual B cells transcribe multiple rearranged immunoglobulin light chains in teleost fish
B cells express a unique antibody protein which comprises two pairs of immunoglobulin (Ig) heavy (H) and light (L) chains. In addition to an invariable constant (C) region, IgH and IgL chains encompass a variable (V) region mediating antigen binding. This unique region stems from Ig V(D)J gene recom...
Autores principales: | Perdiguero, Pedro, Morel, Esther, Díaz-Rosales, Patricia, Tafalla, Carolina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188548/ https://www.ncbi.nlm.nih.gov/pubmed/34142062 http://dx.doi.org/10.1016/j.isci.2021.102615 |
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