Porphyrins produced by acneic Cutibacterium acnes strains activate the inflammasome by inducing K(+) leakage

Some Cutibacterium acnes subgroups dominate on healthy skin, whereas others are frequently acne associated. Here we provide mechanistic insights into this difference, using an anaerobic keratinocyte-sebocyte-C. acnes co-culture model. An acneic C. acnes strain as well as its porphyrins activates NRL...

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Detalles Bibliográficos
Autores principales: Spittaels, Karl-Jan, van Uytfanghe, Katleen, Zouboulis, Christos C., Stove, Christophe, Crabbé, Aurélie, Coenye, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188554/
https://www.ncbi.nlm.nih.gov/pubmed/34151228
http://dx.doi.org/10.1016/j.isci.2021.102575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188554/
https://www.ncbi.nlm.nih.gov/pubmed/34151228
http://dx.doi.org/10.1016/j.isci.2021.102575

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