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Porphyrins produced by acneic Cutibacterium acnes strains activate the inflammasome by inducing K(+) leakage
Some Cutibacterium acnes subgroups dominate on healthy skin, whereas others are frequently acne associated. Here we provide mechanistic insights into this difference, using an anaerobic keratinocyte-sebocyte-C. acnes co-culture model. An acneic C. acnes strain as well as its porphyrins activates NRL...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188554/ https://www.ncbi.nlm.nih.gov/pubmed/34151228 http://dx.doi.org/10.1016/j.isci.2021.102575 |