Dimethyl fumarate reduces hepatocyte senescence following paracetamol exposure

Liver disease is a major cause of premature death. Oxidative stress in the liver represents a key disease driver. Compounds, such as dimethyl fumarate (DMF), can activate the antioxidant response and are used clinically to treat disease. In this study, we tested the protective properties of DMF befo...

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Detalles Bibliográficos
Autores principales: Meseguer-Ripolles, Jose, Lucendo-Villarin, Baltasar, Tucker, Carl, Ferreira-Gonzalez, Sofia, Homer, Natalie, Wang, Yu, Starkey Lewis, Philip J., M Toledo, Enrique, Mellado-Gomez, Esther, Simpson, Joanna, Flint, Oliver, Jaiswal, Himjyot, Beer, Nicola L., Karlsen, Allan E., Forbes, Stuart J., Dear, James W., Hughes, Jeremy, Hay, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188562/
https://www.ncbi.nlm.nih.gov/pubmed/34151225
http://dx.doi.org/10.1016/j.isci.2021.102552

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