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Transcription shapes DNA replication initiation to preserve genome integrity

BACKGROUND: Early DNA replication occurs within actively transcribed chromatin compartments in mammalian cells, raising the immediate question of how early DNA replication coordinates with transcription to avoid collisions and DNA damage. RESULTS: We develop a high-throughput nucleoside analog incor...

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Detalles Bibliográficos
Autores principales:	Liu, Yang, Ai, Chen, Gan, Tingting, Wu, Jinchun, Jiang, Yongpeng, Liu, Xuhao, Lu, Rusen, Gao, Ning, Li, Qing, Ji, Xiong, Hu, Jiazhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188667/ https://www.ncbi.nlm.nih.gov/pubmed/34108027 http://dx.doi.org/10.1186/s13059-021-02390-3

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