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Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children

Recent studies have highlighted relationship of allergic diseases with vitamin D deficiency. The aim of the study was to evaluate the impact of maternal vitamin D levels in pregnancy on the formation of atopic dermatitis in early life. A total of 186 pregnant women and their infants who developed at...

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Autor principal: Petriashvili, Mariam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188965/
https://www.ncbi.nlm.nih.gov/pubmed/34164570
http://dx.doi.org/10.1177/2333794X211022916
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author Petriashvili, Mariam
author_facet Petriashvili, Mariam
author_sort Petriashvili, Mariam
collection PubMed
description Recent studies have highlighted relationship of allergic diseases with vitamin D deficiency. The aim of the study was to evaluate the impact of maternal vitamin D levels in pregnancy on the formation of atopic dermatitis in early life. A total of 186 pregnant women and their infants who developed atopic dermatitis before the age of 2 years were involved in the prospective study. Most pregnant women (57.5%) were diagnosed with 25(OH)D deficiency (3.6 ± 4.4 ng/ml) (P = .000). Maternal 25(OH)D deficiency was directly related to atopic family anamnesis and relatively high IgE levels. In these cases, children developed atopic dermatitis before the age of 6 months (70.8%) with prevalence of moderate-severity (55%) and persistent course (68.3%) of the disease. The above mentioned supported the idea that the peculiarities of the formation of atopic dermatitis in young children are associated with low concentrations of vitamin D in mothers during pregnancy.
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spelling pubmed-81889652021-06-22 Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children Petriashvili, Mariam Glob Pediatr Health Section: Maternal, Newborn, and Child Morbidity and Mortality Recent studies have highlighted relationship of allergic diseases with vitamin D deficiency. The aim of the study was to evaluate the impact of maternal vitamin D levels in pregnancy on the formation of atopic dermatitis in early life. A total of 186 pregnant women and their infants who developed atopic dermatitis before the age of 2 years were involved in the prospective study. Most pregnant women (57.5%) were diagnosed with 25(OH)D deficiency (3.6 ± 4.4 ng/ml) (P = .000). Maternal 25(OH)D deficiency was directly related to atopic family anamnesis and relatively high IgE levels. In these cases, children developed atopic dermatitis before the age of 6 months (70.8%) with prevalence of moderate-severity (55%) and persistent course (68.3%) of the disease. The above mentioned supported the idea that the peculiarities of the formation of atopic dermatitis in young children are associated with low concentrations of vitamin D in mothers during pregnancy. SAGE Publications 2021-06-06 /pmc/articles/PMC8188965/ /pubmed/34164570 http://dx.doi.org/10.1177/2333794X211022916 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Section: Maternal, Newborn, and Child Morbidity and Mortality
Petriashvili, Mariam
Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children
title Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children
title_full Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children
title_fullStr Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children
title_full_unstemmed Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children
title_short Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children
title_sort impact of maternal vitamin d status on the formation of atopic dermatitis in young children
topic Section: Maternal, Newborn, and Child Morbidity and Mortality
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188965/
https://www.ncbi.nlm.nih.gov/pubmed/34164570
http://dx.doi.org/10.1177/2333794X211022916
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