Cargando…
Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children
Recent studies have highlighted relationship of allergic diseases with vitamin D deficiency. The aim of the study was to evaluate the impact of maternal vitamin D levels in pregnancy on the formation of atopic dermatitis in early life. A total of 186 pregnant women and their infants who developed at...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188965/ https://www.ncbi.nlm.nih.gov/pubmed/34164570 http://dx.doi.org/10.1177/2333794X211022916 |
_version_ | 1783705426485837824 |
---|---|
author | Petriashvili, Mariam |
author_facet | Petriashvili, Mariam |
author_sort | Petriashvili, Mariam |
collection | PubMed |
description | Recent studies have highlighted relationship of allergic diseases with vitamin D deficiency. The aim of the study was to evaluate the impact of maternal vitamin D levels in pregnancy on the formation of atopic dermatitis in early life. A total of 186 pregnant women and their infants who developed atopic dermatitis before the age of 2 years were involved in the prospective study. Most pregnant women (57.5%) were diagnosed with 25(OH)D deficiency (3.6 ± 4.4 ng/ml) (P = .000). Maternal 25(OH)D deficiency was directly related to atopic family anamnesis and relatively high IgE levels. In these cases, children developed atopic dermatitis before the age of 6 months (70.8%) with prevalence of moderate-severity (55%) and persistent course (68.3%) of the disease. The above mentioned supported the idea that the peculiarities of the formation of atopic dermatitis in young children are associated with low concentrations of vitamin D in mothers during pregnancy. |
format | Online Article Text |
id | pubmed-8188965 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-81889652021-06-22 Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children Petriashvili, Mariam Glob Pediatr Health Section: Maternal, Newborn, and Child Morbidity and Mortality Recent studies have highlighted relationship of allergic diseases with vitamin D deficiency. The aim of the study was to evaluate the impact of maternal vitamin D levels in pregnancy on the formation of atopic dermatitis in early life. A total of 186 pregnant women and their infants who developed atopic dermatitis before the age of 2 years were involved in the prospective study. Most pregnant women (57.5%) were diagnosed with 25(OH)D deficiency (3.6 ± 4.4 ng/ml) (P = .000). Maternal 25(OH)D deficiency was directly related to atopic family anamnesis and relatively high IgE levels. In these cases, children developed atopic dermatitis before the age of 6 months (70.8%) with prevalence of moderate-severity (55%) and persistent course (68.3%) of the disease. The above mentioned supported the idea that the peculiarities of the formation of atopic dermatitis in young children are associated with low concentrations of vitamin D in mothers during pregnancy. SAGE Publications 2021-06-06 /pmc/articles/PMC8188965/ /pubmed/34164570 http://dx.doi.org/10.1177/2333794X211022916 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Section: Maternal, Newborn, and Child Morbidity and Mortality Petriashvili, Mariam Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children |
title | Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children |
title_full | Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children |
title_fullStr | Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children |
title_full_unstemmed | Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children |
title_short | Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children |
title_sort | impact of maternal vitamin d status on the formation of atopic dermatitis in young children |
topic | Section: Maternal, Newborn, and Child Morbidity and Mortality |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188965/ https://www.ncbi.nlm.nih.gov/pubmed/34164570 http://dx.doi.org/10.1177/2333794X211022916 |
work_keys_str_mv | AT petriashvilimariam impactofmaternalvitamindstatusontheformationofatopicdermatitisinyoungchildren |