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A method for systematically ranking therapeutic drug candidates using multiple uncertain screening criteria
Multiple different screening tests for candidate leads in drug development may often yield conflicting or ambiguous results, sometimes making the selection of leads a nontrivial maximum-likelihood ranking problem. Here, we employ methods from the field of multiple criteria decision making (MCDM) to...
Autores principales: | Peng, Xubiao, Gibbs, Ebrima, Silverman, Judith M, Cashman, Neil R, Plotkin, Steven S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189013/ https://www.ncbi.nlm.nih.gov/pubmed/33847541 http://dx.doi.org/10.1177/09622802211002861 |
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