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A method for systematically ranking therapeutic drug candidates using multiple uncertain screening criteria

Multiple different screening tests for candidate leads in drug development may often yield conflicting or ambiguous results, sometimes making the selection of leads a nontrivial maximum-likelihood ranking problem. Here, we employ methods from the field of multiple criteria decision making (MCDM) to...

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Detalles Bibliográficos
Autores principales: Peng, Xubiao, Gibbs, Ebrima, Silverman, Judith M, Cashman, Neil R, Plotkin, Steven S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189013/
https://www.ncbi.nlm.nih.gov/pubmed/33847541
http://dx.doi.org/10.1177/09622802211002861

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