Innate Immune Reconstitution in Humanized Bone Marrow-Liver-Thymus (HuBLT) Mice Governs Adaptive Cellular Immune Function and Responses to HIV-1 Infection

Humanized bone marrow-liver-thymus (HuBLT) mice are a revolutionary small-animal model that has facilitated the study of human immune function and human-restricted pathogens, including human immunodeficiency virus type 1 (HIV-1). These mice recapitulate many aspects of acute and chronic HIV-1 infect...

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Detalles Bibliográficos
Autores principales: Garcia-Beltran, Wilfredo F., Claiborne, Daniel T., Maldini, Colby R., Phelps, Meredith, Vrbanac, Vladimir, Karpel, Marshall E., Krupp, Katharine L., Power, Karen A., Boutwell, Christian L., Balazs, Alejandro B., Tager, Andrew M., Altfeld, Marcus, Allen, Todd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189152/
https://www.ncbi.nlm.nih.gov/pubmed/34122425
http://dx.doi.org/10.3389/fimmu.2021.667393

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