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Cardiac Mesenchymal Cells Cultured at Physiologic Oxygen Tension Have Superior Therapeutic Efficacy in Heart Failure Caused by Myocardial Infarction
Stem/progenitor cells are usually cultured at atmospheric O(2) tension (21%); however, since physiologic O(2) tension in the heart is ∼5%, using 21% O(2) may cause oxidative stress and toxicity. Cardiac mesenchymal cells (CMCs), a newly discovered and promising type of progenitor cells, are effectiv...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189180/ https://www.ncbi.nlm.nih.gov/pubmed/34124043 http://dx.doi.org/10.3389/fcell.2021.662415 |