Cargando…

Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription

Mostrar otras versiones (1)

Detalles Bibliográficos
Autores principales:	Cossa, Giacomo, Roeschert, Isabelle, Prinz, Florian, Baluapuri, Apoorva, Vidal, Raphael Silveira, Schülein-Völk, Christina, Chang, Yun-Chien, Ade, Carsten Patrick, Mastrobuoni, Guido, Girard, Cyrille, Kumar, Amit, Wortmann, Lars, Walz, Susanne, Lührmann, Reinhard, Kempa, Stefan, Kuster, Bernhard, Wolf, Elmar, Mumberg, Dominik, Eilers, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2021
Materias:	Correction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189434/ https://www.ncbi.nlm.nih.gov/pubmed/34087181 http://dx.doi.org/10.1016/j.molcel.2021.05.013

Ejemplares similares

Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription
por: Cossa, Giacomo, et al.
Publicado: (2020)

Different promoter affinities account for specificity in MYC-dependent gene regulation
por: Lorenzin, Francesca, et al.
Publicado: (2016)

Calcium signalling links MYC to NUAK1
por: Monteverde, T, et al.
Publicado: (2018)

Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle
por: Büchel, Gabriele, et al.
Publicado: (2017)

An unsteady scaffold for Myc
por: Schülein, Christina, et al.
Publicado: (2009)

A MYC/GCN2/eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer
por: Schmidt, Stefanie, et al.
Publicado: (2019)

Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns
por: Keiper, Sandra, et al.
Publicado: (2019)

The Sm-core mediates the retention of partially-assembled spliceosomal snRNPs in Cajal bodies until their full maturation
por: Roithová, Adriana, et al.
Publicado: (2018)

NUAK1 and NUAK2 Fine-Tune TGF-β Signaling
por: van de Vis, Reinofke A. J., et al.
Publicado: (2021)

The spliceosome is a therapeutic vulnerability in MYC-driven cancer
por: Hsu, Tiffany Y-T., et al.
Publicado: (2015)

NUAK Kinases: Brain–Ovary Axis
por: Molina, Ester, et al.
Publicado: (2021)

MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation
por: Baluapuri, Apoorva, et al.
Publicado: (2019)

The spliceosome, a potential Achilles heel of MYC-driven tumors
por: Anczuków, Olga, et al.
Publicado: (2015)

Regulation of 3′ splice site selection after step 1 of splicing by spliceosomal C* proteins
por: Dybkov, Olexandr, et al.
Publicado: (2023)

NUAK2: an emerging acral melanoma oncogene
por: Namiki, Takeshi, et al.
Publicado: (2011)

NUAK1 links genomic instability and senescence
por: Bernard, David, et al.
Publicado: (2010)

A Stochastic View of Spliceosome Assembly and Recycling in the Nucleus
por: Rino, José, et al.
Publicado: (2007)

The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome
por: Warkocki, Zbigniew, et al.
Publicado: (2015)

A protein map of the yeast activated spliceosome as obtained by electron microscopy
por: Sun, Chengfu, et al.
Publicado: (2016)

Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination
por: Narain, Ashwin, et al.
Publicado: (2021)

Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28
por: Möhlmann, Sina, et al.
Publicado: (2014)

Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells
por: Prieto‐Garcia, Cristian, et al.
Publicado: (2020)

Inhibition of growth and contraction in human prostate stromal cells by silencing of NUAK1 and -2, and by the presumed NUAK inhibitors HTH01-015 and WZ4003
por: Liu, Yuhan, et al.
Publicado: (2023)

NUAK2 is a critical YAP target in liver cancer
por: Yuan, Wei-Chien, et al.
Publicado: (2018)

The RES complex is required for efficient transformation of the precatalytic B spliceosome into an activated B(act) complex
por: Bao, Penghui, et al.
Publicado: (2017)

Muscle-specific Knock-out of NUAK Family SNF1-like Kinase 1 (NUAK1) Prevents High Fat Diet-induced Glucose Intolerance
por: Inazuka, Fumika, et al.
Publicado: (2012)

SUMO conjugation to spliceosomal proteins is required for efficient pre-mRNA splicing
por: Pozzi, Berta, et al.
Publicado: (2017)

Potential effect of spliceosome inhibition in small cell lung cancer irrespective of the MYC status
por: Suda, Kenichi, et al.
Publicado: (2017)

Regulation of Prp43-mediated disassembly of spliceosomes by its cofactors Ntr1 and Ntr2
por: Fourmann, Jean-Baptiste, et al.
Publicado: (2017)

The importin-β binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitro
por: Huber, Jochen, et al.
Publicado: (2002)

ATPγS stalls splicing after B complex formation but prior to spliceosome activation
por: Agafonov, Dmitry E., et al.
Publicado: (2016)

NUAK1 (ARK5) Is Associated with Poor Prognosis in Ovarian Cancer
por: Phippen, Neil T., et al.
Publicado: (2016)

Drosophila NUAK functions with Starvin/BAG3 in autophagic protein turnover
por: Brooks, David, et al.
Publicado: (2020)

RNA polymerase I inhibition induces terminal differentiation, growth arrest, and vulnerability to senolytics in colorectal cancer cells
por: Otto, Christoph, et al.
Publicado: (2022)

Spliceosome Database: a tool for tracking components of the spliceosome
por: Cvitkovic, Ivan, et al.
Publicado: (2013)

Gene expression profiling of NUAK kinase overexpression in Drosophila larval muscle development
por: Brooks, David, et al.
Publicado: (2022)

Multiple RNA–RNA tertiary interactions are dispensable for formation of a functional U2/U6 RNA catalytic core in the spliceosome
por: Bao, Penghui, et al.
Publicado: (2018)

Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly
por: Jagtap, Pravin Kumar Ankush, et al.
Publicado: (2020)

Structures of the human pre-catalytic spliceosome and its precursor spliceosome
por: Zhan, Xiechao, et al.
Publicado: (2018)

Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation
por: Sidarovich, Anzhalika, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_kbpqnni1s38auv0othefoslqms