G2S3: A gene graph-based imputation method for single-cell RNA sequencing data

Single-cell RNA sequencing technology provides an opportunity to study gene expression at single-cell resolution. However, prevalent dropout events result in high data sparsity and noise that may obscure downstream analyses in single-cell transcriptomic studies. We propose a new method, G2S3, that i...

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Detalles Bibliográficos
Autores principales: Wu, Weimiao, Liu, Yunqing, Dai, Qile, Yan, Xiting, Wang, Zuoheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189489/
https://www.ncbi.nlm.nih.gov/pubmed/34003861
http://dx.doi.org/10.1371/journal.pcbi.1009029

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