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Necrotizing Cellulitis and Myositis in a Neutropenic Leukemic Patient

In this article, we review a case of necrotizing cellulitis and myositis in a neutropenic leukemic patient. He underwent a series of investigations to reach the diagnosis of pyoderma gangrenosum (PG). The lesion improved dramatically after pertinent identification and initiation of appropriate treat...

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Detalles Bibliográficos
Autores principales: Alok, Akankcha, Greene, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189531/
https://www.ncbi.nlm.nih.gov/pubmed/34123638
http://dx.doi.org/10.7759/cureus.14941
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author Alok, Akankcha
Greene, John
author_facet Alok, Akankcha
Greene, John
author_sort Alok, Akankcha
collection PubMed
description In this article, we review a case of necrotizing cellulitis and myositis in a neutropenic leukemic patient. He underwent a series of investigations to reach the diagnosis of pyoderma gangrenosum (PG). The lesion improved dramatically after pertinent identification and initiation of appropriate treatment. The management of PG is exceedingly challenging due to a lack of proper clinical criteria for detection and guidelines for treatment. PG must be considered as a differential in patients with enlarging, sterile, necrotic lesions, unresponsive to prolonged broad-spectrum antibiotics. Prompt recognition can prevent deeper infections and the formation of a chronic open wound causing cosmetic disfigurement along with other catastrophic complications.
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spelling pubmed-81895312021-06-10 Necrotizing Cellulitis and Myositis in a Neutropenic Leukemic Patient Alok, Akankcha Greene, John Cureus Dermatology In this article, we review a case of necrotizing cellulitis and myositis in a neutropenic leukemic patient. He underwent a series of investigations to reach the diagnosis of pyoderma gangrenosum (PG). The lesion improved dramatically after pertinent identification and initiation of appropriate treatment. The management of PG is exceedingly challenging due to a lack of proper clinical criteria for detection and guidelines for treatment. PG must be considered as a differential in patients with enlarging, sterile, necrotic lesions, unresponsive to prolonged broad-spectrum antibiotics. Prompt recognition can prevent deeper infections and the formation of a chronic open wound causing cosmetic disfigurement along with other catastrophic complications. Cureus 2021-05-10 /pmc/articles/PMC8189531/ /pubmed/34123638 http://dx.doi.org/10.7759/cureus.14941 Text en Copyright © 2021, Alok et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Alok, Akankcha
Greene, John
Necrotizing Cellulitis and Myositis in a Neutropenic Leukemic Patient
title Necrotizing Cellulitis and Myositis in a Neutropenic Leukemic Patient
title_full Necrotizing Cellulitis and Myositis in a Neutropenic Leukemic Patient
title_fullStr Necrotizing Cellulitis and Myositis in a Neutropenic Leukemic Patient
title_full_unstemmed Necrotizing Cellulitis and Myositis in a Neutropenic Leukemic Patient
title_short Necrotizing Cellulitis and Myositis in a Neutropenic Leukemic Patient
title_sort necrotizing cellulitis and myositis in a neutropenic leukemic patient
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189531/
https://www.ncbi.nlm.nih.gov/pubmed/34123638
http://dx.doi.org/10.7759/cureus.14941
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