Stable but not rigid: Chronic in vivo STED nanoscopy reveals extensive remodeling of spines, indicating multiple drivers of plasticity

Excitatory synapses on dendritic spines of pyramidal neurons are considered a central memory locus. To foster both continuous adaption and the storage of long-term information, spines need to be plastic and stable at the same time. Here, we advanced in vivo STED nanoscopy to superresolve distinct fe...

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Detalles Bibliográficos
Autores principales: Steffens, Heinz, Mott, Alexander C., Li, Siyuan, Wegner, Waja, Švehla, Pavel, Kan, Vanessa W. Y., Wolf, Fred, Liebscher, Sabine, Willig, Katrin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189587/
https://www.ncbi.nlm.nih.gov/pubmed/34108204
http://dx.doi.org/10.1126/sciadv.abf2806

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