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Sp1 Targeted PARP1 Inhibition Protects Cardiomyocytes From Myocardial Ischemia–Reperfusion Injury via Downregulation of Autophagy

Myocardial ischemia–reperfusion injury (MIRI), characterized by post-ischemic cardiomyocytes death and reperfusion myocardial damage, is a lethal yet unresolved complication in the treatment of acute myocardial infarction (AMI). Previous studies have demonstrated that poly(ADP-ribose) polymerase-1 (...

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Detalles Bibliográficos
Autores principales:	Xu, Yifeng, Wang, Boqian, Liu, Xiaoxiao, Deng, Yunfei, Zhu, Yanqi, Zhu, Feng, Liang, Yanyan, Li, Hongli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190009/ https://www.ncbi.nlm.nih.gov/pubmed/34124031 http://dx.doi.org/10.3389/fcell.2021.621906

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