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Follicular helper-T cells restore CD8(+)-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy

BACKGROUND: T follicular helper cells (Tfh) are essential to shape B cell response during germinal center formation. Tfh accumulation has been reported in various human cancers, with positive or negative prognostic roles. However, the mechanisms explaining the accumulation of Tfh and their role in c...

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Detalles Bibliográficos
Autores principales:	Niogret, Julie, Berger, Hélène, Rebe, Cédric, Mary, Romain, Ballot, Elise, Truntzer, Caroline, Thibaudin, Marion, Derangère, Valentin, Hibos, Christophe, Hampe, Léa, Rageot, David, Accogli, Théo, Joubert, Philippe, Routy, Bertrand, Harker, James, Vegran, Frederique, Ghiringhelli, Francois, Chalmin, Fanny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190041/ https://www.ncbi.nlm.nih.gov/pubmed/34103351 http://dx.doi.org/10.1136/jitc-2020-002157

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